4-C-Hydroxymethyl-2,3-O-isopropylidene-1-O-methyl-beta-D-ribofuranose Chemical Properties

Melting point:

94-95 °C (decomp)(Solv: cyclohexane (110-82-7))

Boiling point:

349.3±42.0 °C(Predicted)

Density 

1.30±0.1 g/cm3(Predicted)

pka

13.83±0.10(Predicted)

4-C-Hydroxymethyl-2,3-O-isopropylidene-1-O-methyl-beta-D-ribofuranose Usage And Synthesis

Uses

Methyl 4-C-hydroxymethyl-2,3-O-isopropylidene-beta-D-ribofuranoside is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

References

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005