Glutaminyl Cyclase Inhibitor 1
Glutaminyl Cyclase Inhibitor 1 Basic information
- Product Name:
- Glutaminyl Cyclase Inhibitor 1
- Synonyms:
-
- Glutaminyl Cyclase Inhibitor 1
- 1H-Imidazole-1-propanamine, N-(3-fluoro-3',4'-dimethoxy[1,1'-biphenyl]-2-yl)-4-methyl-
- Glutaminyl Cyclase Inhibitor 1, 10 mM in DMSO
- CAS:
- 2110449-60-8
- MF:
- C21H24FN3O2
- MW:
- 369.43
- Mol File:
- 2110449-60-8.mol
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Glutaminyl Cyclase Inhibitor 1 Chemical Properties
- Boiling point:
- 568.3±50.0 °C(Predicted)
- Density
- 1.15±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO : 83.33 mg/mL (225.56 mM)
- pka
- 7.49±0.61(Predicted)
- form
- Solid
- color
- White to yellow
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Glutaminyl Cyclase Inhibitor 1 Usage And Synthesis
Uses
Glutaminyl Cyclase Inhibitor 1 is a glutaminyl cyclase inhibitor with an IC50 of 0.5 μM.
Biological Activity
Glutaminyl Cyclase Inhibitor 1 is a glutaminyl cyclase inhibitor with IC50 of 0.5 μM.
in vitro
Glutaminyl Cyclase Inhibitor 1 is compound 23.
target
IC50: 0.5 μM (Glutaminyl cyclase)
References
[1] Li M, et al. Synthesis and Evaluation of Diphenyl Conjugated Imidazole Derivatives as Potential Glutaminyl Cyclase Inhibitors for Treatment of Alzheimer's Disease. J Med Chem. 2017 Aug 10;60(15):6664-6677. DOI:10.1021/acs.jmedchem.7b00648
Glutaminyl Cyclase Inhibitor 1Supplier
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