Peanut procyanidin A
Peanut procyanidin A Basic information
- Product Name:
- Peanut procyanidin A
- Synonyms:
-
- Peanut procyanidin A
- 8,14-Methano-2H,14H-[1,3]benzodioxocino[4,5-h]-1-benzopyran-3,5,11,13,15-pentol, 2,8-bis(3,4-dihydroxyphenyl)-10-[(2S,3S,4R)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-3,5,7-trihydroxy-2H-1-benzopyran-4-yl]-3,4-dihydro-, (2R,3S,8R,14R,15R)-
- CAS:
- 1802175-67-2
- MF:
- C45H36O18
- MW:
- 864.76
- Mol File:
- 1802175-67-2.mol
Peanut procyanidin A Chemical Properties
- Density
- 1.789±0.06 g/cm3(Predicted)
- pka
- 9.02±0.70(Predicted)
Peanut procyanidin A Usage And Synthesis
Uses
Peanut procyanidin A is a type of A-type procyanidin that can be extracted from peanut skins. Peanut procyanidin A can protect prostate DU145 cells from H2O2-induced oxidative stress damage through the MAPKs signaling pathway, alleviate cell cycle arrest, and reduce cell apoptosis. Peanut procyanidin A can also regulate gut microbiota and metabolism in mice with DSS (HY-116282)-induced ulcerative colitis[1][2].
References
[1] Yan F, et al. Protective effect of procyanidin A-type dimers against H2O2-induced oxidative stress in prostate DU145 cells through the MAPKs signaling pathway. Life Sci. 2021 Feb 1;266:118908. DOI:10.1016/j.lfs.2020.118908
[2] Huang B, et al. The underlying mechanism of A-type procyanidins from peanut skin on DSS-induced ulcerative colitis mice by regulating gut microbiota and metabolism. J Food Biochem. 2022 Jul;46(7):e14103. DOI:10.1111/jfbc.14103
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