DAU 5884 hydrochloride
DAU 5884 hydrochloride Basic information
- Product Name:
- DAU 5884 hydrochloride
- Synonyms:
-
- 8-Methyl-8-azabicyclo-3-endo[3.2.1]oct-3-yl-1,4-dihydro-2-oxo-3(2H)-quinazolinecarboxylic acid ester hydrochloride
- (1R,5S)-rel-8-Methyl-8-azabicyclo[3.2.1]octan-3-yl 2-oxo-1,2-dihydroquinazoline-3(4H)-carboxylate hydrochloride
- DAU 5884 hydrochloride, M3 receptor antagonist
- CAS:
- 131780-48-8
- MF:
- C17H22ClN3O3
- MW:
- 351.83
- Mol File:
- 131780-48-8.mol
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DAU 5884 hydrochloride Chemical Properties
- storage temp.
- Store at -20°C
- solubility
- Soluble to 50 mM in water and to 100 mM in DMSO
- form
- Powder
- color
- White to off-white
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DAU 5884 hydrochloride Usage And Synthesis
Description
Selective muscarinic M3 receptor antagonist. In bovine tracheal smooth muscle, inhibits methacholine-dependent effects on cell proliferation and muscle contractility.
Uses
DAU 5884 hydrochloride is a potent muscarinic M3 receptor antagonist. DAU 5884 hydrochloride inhibits methacholine-dependent effects on cell proliferation and muscle contractility[1].
storage
Desiccate at +4°C
References
[1] Gosens R, et, al. Muscarinic M3-receptors mediate cholinergic synergism of mitogenesis in airway smooth muscle. Am J Respir Cell Mol Biol. 2003 Feb;28(2):257-62. DOI:10.1165/rcmb.2002-0128OC
DAU 5884 hydrochlorideSupplier
TargetMol Chemicals Inc.
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BOC Sciences
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TargetMol Chemicals Inc.
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Nantong QuanYi Biotechnology Co., Ltd
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