Fmoc-L-Photo-Leucine Chemical Properties

Density 

1.41±0.1 g/cm3(Predicted)

storage temp. 

2-8°C

pka

3.67±0.10(Predicted)

form 

powder

color 

White to off-white

Safety Information

HS Code 

2933998090

Fmoc-L-Photo-Leucine Usage And Synthesis

Uses

Fmoc-L-Photo-Leucine is a diazirine-containing, Fmoc-protected leucine amino acid and multifunctional photo-crosslinker. Its incorporation into peptides or small-molecule probes and tools allows for photoaffinity labeling of cellular targets and protein-protein interactions upon UV light (～360 nm) irradiation to form a covalent bond. This and other multifunctional probe building blocks will continue to accelerate drug discovery research for probing cellular mechanisms, target ID/validation, and understanding traditionally undruggable targets. An unprotected version is also available as 907278.

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis