Basic information Safety Supplier Related

4-PHENOXYBENZYLAMINE

Basic information Safety Supplier Related

4-PHENOXYBENZYLAMINE Basic information

Product Name:
4-PHENOXYBENZYLAMINE
Synonyms:
  • RARECHEM AL BW 0345
  • 4-PHENOXYBENZYLAMINE
  • (4-PHENOXYPHENYL)METHYLAMINE
  • AKOS B022085
  • 4-Phenyloxybenzylamine
  • 4-Phenoxybenzenemethanamine
  • ART-CHEM-BB B022085
  • BenzeneMethanaMine, 4-phenoxy-
CAS:
107622-80-0
MF:
C13H13NO
MW:
199.25
Product Categories:
  • Anilines, Aromatic Amines and Nitro Compounds
Mol File:
107622-80-0.mol
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4-PHENOXYBENZYLAMINE Chemical Properties

Boiling point:
138°C 5mm
Density 
1,12 g/cm3
refractive index 
1.59
Flash point:
150℃
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Soluble in DMSO
form 
clear liquid
pka
9.13±0.10(Predicted)
color 
Colorless to Light orange to Yellow
CAS DataBase Reference
107622-80-0(CAS DataBase Reference)
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Safety Information

Hazard Codes 
C,Xi,N,T
Risk Statements 
36/37/38-50-41-37/38-25
Safety Statements 
26-36/37/39-61-45-39
RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
3
HazardClass 
IRRITANT, IRRITANT-HARMFUL
HS Code 
2922290090
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4-PHENOXYBENZYLAMINE Usage And Synthesis

Biological Activity

4-Phenoxybenzylamine inhibits the function of NS3 protein by stabilizing the inactive conformation, and inhibits FL NS3/4a with an IC50 value of approximately 500 μM.

in vitro

A highly conserved novel binding site located at the interface between the protease and helicase domains of the Hepatitis C Virus (HCV) NS3 protein is identified. 4-Phenoxybenzylamine binding at this allosteric site inhibits the function of the NS3 protein by stabilizing an inactive conformation and thus represents a new class of direct acting antiviral agents.

target

IC50: 500 μM (FL NS3/4a)

4-PHENOXYBENZYLAMINESupplier

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