MSX-2
MSX-2 Basic information
- Product Name:
- MSX-2
- Synonyms:
-
- 3-(3-Hydroxypropyl)-8-(m-methoxystyryl)-7-methyl-1-propargylxanthine
- 1H-Purine-2,6-dione, 3,7-dihydro-3-(3-hydroxypropyl)-8-[(1E)-2-(3-methoxyphenyl)ethenyl]-7-methyl-1-(2-propyn-1-yl)-
- 3-(3-hydroxypropyl)-8-[(E)-2-(3-methoxyphenyl)ethenyl]-7-methyl-1-prop-2-ynylpurine-2,6-dione
- CAS:
- 261717-18-4
- MF:
- C21H22N4O4
- MW:
- 394.42
- Mol File:
- 261717-18-4.mol
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MSX-2 Chemical Properties
- storage temp.
- −20°C
- solubility
- DMSO: ~14 mg/mL
- form
- solid
- color
- pale yellow
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MSX-2 Usage And Synthesis
Uses
MSX-2 is A2A adenosine receptor antagonist, with Ki of 5 nM in human that plays an important role in Parkinson's disease[1][2].
References
[1] Manuel de Lera Ruiz, et al. Adenosine A2A Receptor as a Drug Discovery Target. J Med Chem. 2014 May 8;57(9):3623-50. DOI:10.1021/jm4011669
[2] Tina Becic, et al. Growth factors FGF8 and FGF2 and their receptor FGFR1, transcriptional factors Msx-1 and MSX-2, and apoptotic factors p19 and RIP5 participate in the early human limb development. Acta Histochem. 2018 Apr;120(3):205-214. DOI:10.1016/j.acthis.2018.01.008
MSX-2Supplier
TargetMol Chemicals Inc.
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InvivoChem
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Beijing Biocreative Technology Co., Ltd.
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ShenZhen Trendseen Biological Technology Co.,Ltd.
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TargetMol Chemicals Inc.
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- 15002134094
- marketing@targetmol.cn