Basic information Safety Supplier Related

MOEXIPRILAT HYDRATE

Basic information Safety Supplier Related

MOEXIPRILAT HYDRATE Basic information

Product Name:
MOEXIPRILAT HYDRATE
Synonyms:
  • (3S)-2-[(2S)-2-{[(1S)-1-carboxy-3-(2,3,4,5,6-pentahydrogeniophenyl)propyl]amino}propanoyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
  • (3S)-2-[(2S)-2-[[(1S)-1-Carboxy-3-phenylpropyl]aMino]-1-oxopropyl]-1,2,3,4-tetrahydro-6,7-diMethoxy-3-isoquinolinecarboxylic Acid
  • [3S-[2[R*(R*)],3R*]]-2-[2-[(1- Carboxy-3-phenylpropyl)aMino]-1-oxopropyl]-1,2,3,4-tetrahydro-6,7-diMethoxy-3-isoquinolinecarboxylic Acid
  • RS 10029
  • (3S)-2-[(2S)-2-[[(1S)-1-Carboxy-3-(phenyl-d5)propyl]aMino]-1-oxopropyl]-1,2,3,4-tetrahydro-6,7-diMethoxy-3-isoquinolinecarboxylic Acid
  • [3S-[2[R*(R*)],3R*]]-2-[2-[(1- Carboxy-3-(phenyl-d5)propyl)aMino]-1-oxopropyl]-1,2,3,4-tetrahydro-6,7-diMethoxy-3-isoquinolinecarboxylic Acid
  • Moexipril Related CoMpound A
  • 2-[2-(1-Carboxy-3-phenyl-propylamino)-propionyl]-6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic Acid Hydrate
CAS:
103775-14-0
MF:
C25H30N2O7
MW:
470.51
Product Categories:
  • All Inhibitors
  • Inhibitors
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Aromatics
  • Chiral Reagents
Mol File:
103775-14-0.mol
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MOEXIPRILAT HYDRATE Chemical Properties

Melting point:
145-1700C
storage temp. 
Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility 
DMSO: soluble
Methanol: soluble
Major Application
pharmaceutical
InChIKey
CMPAGYDKASJORH-YSSFQJQWSA-N
SMILES
N2([C@@H](Cc3c(cc(c(c3)OC)OC)C2)C(=O)O)C(=O)[C@@H](N[C@@H](CCc1ccccc1)C(=O)O)C
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Safety Information

WGK Germany 
WGK 3
HS Code 
2933497050
Storage Class
13 - Non Combustible Solids
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MOEXIPRILAT HYDRATE Usage And Synthesis

Chemical Properties

White Crystalline Solid

Uses

Analogue of Quinapril

Uses

Moexiprilat is an angiotensin converting enzyme (ACE) inhibitor; dimethoxy analog of Quinapril. Antihypertensive.

Uses

Angiotensin converting enzyme (ACE) inhibitor; dimethoxy analog of Quinapril. Antihypertensive.

References

[1] O EDLING. Moexipril, a new angiotensin-converting enzyme (ACE) inhibitor: pharmacological characterization and comparison with enalapril.[J]. Journal of Pharmacology and Experimental Therapeutics, 1995, 275 2: 854-863.
[2] RYAN T. CAMERON . Chemical informatics uncovers a new role for moexipril as a novel inhibitor of cAMP phosphodiesterase-4 (PDE4)[J]. Biochemical pharmacology, 2013, 85 9: Pages 1297-1305. DOI: 10.1016/j.bcp.2013.02.026
[3] C GROHÉ. Angiotensin converting enzyme inhibition modulates cardiac fibroblast growth.[J]. Journal of Hypertension, 1998, 16 3: 377-384. DOI: 10.1097/00004872-199816030-00015
[4] VAN EICKELS MARTIN. The influence of oestrogen-deficiency and ACE inhibition on the progression of myocardial hypertrophy in spontaneously hypertensive rats[J]. European Journal of Heart Failure, 2005, 7 7: 1079-1084. DOI: 10.1016/j.ejheart.2005.03.004

MOEXIPRILAT HYDRATESupplier

J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Email
jkinfo@jkchemical.com
Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Cato Research Chemicals Inc.
Tel
020-81960175
Email
min.he@cato-chem.com
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Email
info@efebio.com
Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
17801761073
Email
3193328036@qq.com
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