5-Amino-1-(3,5-dichloro-4-(4-chlorobenzoyl)benzyl)-1H-1,2,3-triazole-4-carboxamide
5-Amino-1-(3,5-dichloro-4-(4-chlorobenzoyl)benzyl)-1H-1,2,3-triazole-4-carboxamide Basic information
- Product Name:
- 5-Amino-1-(3,5-dichloro-4-(4-chlorobenzoyl)benzyl)-1H-1,2,3-triazole-4-carboxamide
- Synonyms:
-
- 5-Amino-1-[3,5-dichloro-4-(4-chlorobenzoyl)benzyl]-1H-[1,2,3]triazole-4-carboxylic acid amide
- 1H-1,2,3-TRIAZOLE-4-CARBOXAMIDE-5-AMINO-1-[[3,5-DICHLORO-4-(4-CHLOROBENZOYL)PHENYL]METHYL]
- carboxyamido-triazole
- 5-Amino-1-(3,5-dichloro-4-(4-chlorobenzoyl)benzyl)-1H-1,2,3-triazole-4-carboxamide
- 1-[3,5-Dichloro-4-(4-chlorobenzoyl)benzyl]-5-amino-1H-1,2,3-triazole-4-carboxamide
- 5-Amino-1-[4-(4-chlorobenzoyl)-3,5-dichlorobenzyl]-1H-1,2,3-triazole-4-carboxamide
- L-651582
- carboxyaMido-triazole(5-AMino-1-(3,5-dichloro-4-(4-chlorobenzoyl)benzyl)-1H-1,2,3-triazole-4-carboxaMide)
- CAS:
- 99519-84-3
- MF:
- C17H12Cl3N5O2
- MW:
- 424.67
- Mol File:
- 99519-84-3.mol
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5-Amino-1-(3,5-dichloro-4-(4-chlorobenzoyl)benzyl)-1H-1,2,3-triazole-4-carboxamide Chemical Properties
- Melting point:
- 200-202 °C
- Boiling point:
- 685.5±65.0 °C(Predicted)
- Density
- 1.65±0.1 g/cm3(Predicted)
- storage temp.
- Store at +4°C
- solubility
- DMSO: soluble10mg/mL (clear solution)
- form
- powder
- pka
- 14.16±0.50(Predicted)
- color
- white to beige
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5-Amino-1-(3,5-dichloro-4-(4-chlorobenzoyl)benzyl)-1H-1,2,3-triazole-4-carboxamide Usage And Synthesis
Uses
Carboxyamidotriazole is an orally active calcium channel blocker. Carboxyamidotriazole also exhibits inhibition of pro-inflammatory cytokines in tumor associated macrophages as potential anti-cancer m echanism.
Biological Activity
Orally active Ca 2+ channel blocker; inhibits K + - and carbachol-stimulated Ca 2+ influx (IC 50 values are 500 and 935 nM respectively). Exhibits antiproliferative, antiangiogenic and antimetastatic activity in vivo and displays selectivity towards numerous mismatch repair-deficient tumor cell lines in vitro .
storage
Store at +4°C
5-Amino-1-(3,5-dichloro-4-(4-chlorobenzoyl)benzyl)-1H-1,2,3-triazole-4-carboxamideSupplier
J & K SCIENTIFIC LTD.
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Chemsky（shanghai）International Co.,Ltd.
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- 021-50135380
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5-Amino-1-(3,5-dichloro-4-(4-chlorobenzoyl)benzyl)-1H-1,2,3-triazole-4-carboxamide(99519-84-3)Related Product Information
- Benzoyl peroxide
- Chlorantraniliprole
- Benzyl chloride
- Benzyl acetate
- Sodium carboxymethyl cellulose
- 1H-Benzotriazole
- N,N-Dimethylformamide
- Benzyl alcohol
- 1,2,4-Triazole
- Formamide
- Benzyl benzoate
- Benzyl
- 4-ISOCYANATO-1-(TRIFLUOROACETYL)PIPERIDINE
- 2-Chloro-4-methylbenzaldehyde
- 2',6'-Dichloroacetophenone
- 3-Chloro-4-methylbenzylamine
- 2,4'-Dichlorobenzophenone
- 4-METHYL-1-PHENYLMETHYL-1H-1,2,3-TRIAZOLE