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MC-Gly-Gly-Phe

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MC-Gly-Gly-Phe Basic information

Product Name:
MC-Gly-Gly-Phe
Synonyms:
  • MC-Gly-Gly-Phe
  • L-Phenylalanine, N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]glycylglycyl-
  • MC-GGF
  • (2S)-2-[[2-[[2-[6-(2,5-dioxopyrrol-1-yl)hexanoylamino]acetyl]amino]acetyl]amino]-3-phenylpropanoic acid
  • Inhibitor,inhibit,MCGlyGlyPhe,MC Gly Gly Phe,Antibody-drug conjugates linkers,ADC Linkers
  • N-[6-(2,5-Dihydro-2,5-Dioxo-1H-Pyrrol-1-Yl)-1-Oxohexyl]Glycylglycyl-L-Ghenylalanine
  • (S)-2-[2-[2-[6-(2,5-Dioxo-2,5-dihydro-1-pyrrolyl)hexanamido]acetamido]acetamido]-3-phenylpropanoic Acid
  • (2S)-2-(2-(2-(6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanamido)acetamido)acetamido)-3-phenylpropanoic acid
CAS:
1599440-15-9
MF:
C23H28N4O7
MW:
472.49
Product Categories:
  • ADCs Linkers
  • ADC
  • ADC LINKER
  • ADCs
Mol File:
1599440-15-9.mol
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MC-Gly-Gly-Phe Chemical Properties

Boiling point:
877.3±65.0 °C(Predicted)
Density 
1.317±0.06 g/cm3(Predicted)
storage temp. 
Storage temp. 2-8°C
form 
Solid
pka
3.49±0.10(Predicted)
color 
White to off-white
InChIKey
NFVPAFLSJIPUCL-KRWDZBQOSA-N
SMILES
C(O)(=O)[C@H](CC1=CC=CC=C1)NC(=O)CNC(=O)CNC(=O)CCCCCN1C(=O)C=CC1=O
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MC-Gly-Gly-Phe Usage And Synthesis

Chemical Properties

White to off-white Solid

Uses

MC-Gly-Gly-Phe is a cleavable linker used for antibody-drug conjugates (ADC).

IC 50

Cleavable Linker

MC-Gly-Gly-PheSupplier

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