KYOTORPHIN Chemical Properties

Density 

1.43±0.1 g/cm3(Predicted)

storage temp. 

-20°C

solubility 

H2O: soluble20mg/mL, clear

pka

3.09±0.10(Predicted)

form 

powder

color 

white to beige

Water Solubility 

H2O: 20mg/mL, clear

KYOTORPHIN Usage And Synthesis

Definition

ChEBI: Tyr-Arg is a dipeptide composed of L-tyrosine and L-arginine joined by a peptide linkage. It is a conjugate base of a L-tyrosiniumyl-L-arginine(1+).

Biological Activity

Kyotorphin is a neuroactive dipeptide (Tyr-Arg) shown to have analgesic, neuroprotective, and neuromodulatory properties. It is synthesized in nerve terminals and found in the brain and in cerebro-spinal fluid (CSF). Kyotorphin indirectly stimulates opioid receptors by releasing methionine enkephalin (met-enkephalin). CSF levels are lower in patients with persistent pain and in patients with Alzheimer′s disease.

KYOTORPHIN(70904-56-2)Related Product Information

• CREBTIDE
• ARG-PRO-PRO-GLY-PHE-SER-PRO-TYR-ARG
• BIOTIN-KRREILSRRPSYR
• 5-TMR-KRREILSRRPSYR
• KYOTORPHIN
• 5-FAM-KRREILSRRPSYR
• GLY-GLY-TYR-ARG
• H2N-ATGGYR-OH
• H-GLU-GLU-ALA-PRO-SER-LEU-ARG-PRO-ALA-PRO-PRO-PRO-ILE-SER-GLY-GLY-GLY-TYR-ARG-OH
• (TYR9)-KALLIDIN
• ABZ-TBU-GLY-TBU-GLY-ASN(ME)2-ALA-SER-SER-ARG-LEU-3-NITRO-TYR-ARG-OH
• neo-kyotorphin
• KYOTORPHIN (D-ARG2),[D-ARG2]-KYOTORPHIN
• (D-arg2)-kyotorphin acetate,kyotorphin (D-Arg)
• Kyotorphin [Neo]
• (D-ARG2)-KYOTORPHIN,(D-ARG2)-KYOTORPHIN ACETATE SALT
• NEO-KYOTORPHIN
• GLU-SER-ALA-ASN-LEU-GLY-GLU-GLU-ILE-LEU-SER-GLN-LEU-TYR-ARG