3'-DC CEP
3'-DC CEP Basic information
- Product Name:
- 3'-DC CEP
- Synonyms:
-
- 3'-DC CEP
- N6-Benzoyl-5'-O-DMT-3'-deoxycytidine 2'-CE phosphoramidite
- N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-deoxycytidine 2'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]
- 4-N-benzoyl-3'-deoxy-5'-O-(4,4'-dimethoxytrityl)cytidine 2-cyanoethyl N,N-diisopropylphosphoramidite
- 3'-dC(Bz)-2'-phosphor amidite
- N6-Benzoyl-3'-deoxy-5'-O-DMT-cytidine 2'-CE phosphoramidite
- Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-deoxy-, 2'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] (9CI)
- N4-Benzoyl-5’-O-(4,4-dimethoxytrityl)-3’-deoxycytidine-2’-CED-phosphoramidite
- CAS:
- 157327-96-3
- MF:
- C46H52N5O8P
- MW:
- 833.91
- Mol File:
- 157327-96-3.mol
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3'-DC CEP Chemical Properties
- solubility
- DMSO: Sparingly Soluble: 1-10 mg/ml
Ethanol: Sparingly Soluble: 1-10 mg/ml - pka
- 8.58±0.20(Predicted)
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3'-DC CEP Usage And Synthesis
Uses
3’-dC(Bz)-2’-phosphor amidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
References
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
[2] ERANDE N, GUNJAL A D, FERNANDES M, et al. Synthesis and structural studies of S-type/N-type-locked/frozen nucleoside analogues and their incorporation in RNA-selective, nuclease resistant 2′–5′ linked oligonucleotides†[J]. Organic & Biomolecular Chemistry, 2012, 5: 746-757. DOI: 10.1039/c2ob26762d
3'-DC CEPSupplier
Nanjing Chemlin Chemical Co., Ltd
- Tel
- 025-83697070
- info@chemlin.com.cn
Bide Pharmatech Ltd.
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- 400-164-7117 13681763483
- product02@bidepharm.com
Shandong utilizing biological technology co., LTD
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- 15966937598
- 3407650895@qq.com
Zhengzhou Granlen Sciences, ltd.
- Tel
- 0371-85513397 +86-18610099868
- info@granlen.com
NewCan Biotech Limited
- Tel
- +86-0571-86912261 +8613735419629
- sales@newcanbio.com