magnesium [(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]methanesulphonate
magnesium [(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]methanesulphonate Basic information
- Product Name:
- magnesium [(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]methanesulphonate
- Synonyms:
-
- magnesium [(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]methanesulphonate
- MAGNESIUM BIS[(2,3-DIHYDRO-1,5-DIMETHYL-3-OXO-2-PHENYL-1H-PYRAZOL-4-YL)METHYLAMINO]METHANESULFONATE
- Dipyrone magnesium
- Bis[[(2,3-dimethyl-1-phenyl-5-oxo-3-pyrazolin-4-yl)(methyl)amino]methanesulfonic acid] magnesium
- Dopirol
- Gewalgin
- Magnopyrol
- Piraken
- CAS:
- 6150-97-6
- MF:
- C26H32MgN6O8S2
- MW:
- 645.00268
- EINECS:
- 2281614
- Mol File:
- 6150-97-6.mol
magnesium [(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]methanesulphonate Usage And Synthesis
Uses
Metamizole (Dipyrone) hemimagnesium is an anti-inflammatory and antioxidant agent with the property of reducing body temperature. Metamizole hemimagnesium can decrease the levels of C-reactive protein (CRP) and interleukin 6 (IL-6). It is also an orally active cyclooxygenase (COX) inhibitor. Metamizole hemimagnesium can inhibit cell proliferation and promote apoptosis. It can be used in the research of inflammation and fever[1].
References
[1] Gozzoli V, et al. Randomized trial of the effect of antipyresis by metamizol, propacetamol or external cooling on metabolism, hemodynamics and inflammatory response. Intensive Care Med. 2004 Mar;30(3):401-7.
[2] Cift?i M, et al. Effects of metamizol and magnesium sulfate on enzyme activity of glucose 6-phosphate dehydrogenase from human erythrocyte in vitro and rat erythrocyte in vivo. Clin Biochem. 2001 Jun;34(4):297-302. DOI:10.1016/s0009-9120(01)00207-7
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