cimoxatone
cimoxatone Basic information
- Product Name:
- cimoxatone
- Synonyms:
-
- 3-[[4-[5-(Methoxymethyl)-2-oxooxazolidin-3-yl]phenoxy]methyl]benzonitrile
- MD-780515
- 3-[[4-[5-(methoxymethyl)-2-oxo-1,3-oxazolidin-3-yl]phenoxy]methyl]benzonitrile
- cimoxatone
- Benzonitrile, 3-[[4-[5-(methoxymethyl)-2-oxo-3-oxazolidinyl]phenoxy]methyl]-
- CAS:
- 73815-11-9
- MF:
- C19H18N2O4
- MW:
- 338.36
- EINECS:
- 2776137
- Mol File:
- 73815-11-9.mol
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cimoxatone Chemical Properties
- Boiling point:
- 474.51°C (rough estimate)
- Density
- 1.2855 (rough estimate)
- refractive index
- 1.6140 (estimate)
- pka
- 0.25±0.40(Predicted)
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cimoxatone Usage And Synthesis
Uses
Cimoxatone is a monoamine oxidase form A (MAO-A) selective inhibitor which shows adverse effects in combination with Tyramine.
in vivo
Cimoxatone (20 mg/kg; p.o.) enhances the anorectic action of 5-HT (1 mg/kg; s.c.) in rats[1].
| Animal Model: | 250-300 g, Adult male Wistar rats[1] |
| Dosage: | 20 mg/kg |
| Administration: | P.o. |
| Result: | Significiantly reduced sucrose intake induced by 1 mg/kg 5-HT or its vehicle injected 2 and 24 h later, significantly enhanced the anorectic action of 5-HT at 2 h but not at 24 h. |
IC 50
MAO-A
cimoxatoneSupplier
TargetMol Chemicals Inc.
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Shaanxi Dideu Medichem Co. Ltd
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- +86-029-81138252 +86-173 9270 1263
- 1057@dideu.com
TargetMol Chemicals Inc.
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- 15002134094
- marketing@targetmol.cn
Zibo Hangyu Biotechnology Development Co., Ltd
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- +86-0533-2185556 +8615965530500
- nickzhang@hangyubiotech.com
Shaanxi Didu New Materials Co. Ltd
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- +86-89586680 +86-13289823923
- 1026@dideu.com