2-Methyl-4-nitroindole Chemical Properties

Melting point:

192-194 °C

Boiling point:

365.6±22.0 °C(Predicted)

Density 

1.355±0.06 g/cm3(Predicted)

storage temp. 

Sealed in dry,Room Temperature

pka

15.34±0.30(Predicted)

Safety Information

Hazard Codes 

Xi

HazardClass 

IRRITANT

HS Code 

2933998090

2-Methyl-4-nitroindole Usage And Synthesis

Uses

2-Methyl-4-nitroindole is a useful synthetic intermediate in the synthesis of AZD1981, a CRTH2 receptor antagonist used in patients with moderate to severe COPD. 2-Methyl-4-nitroindole is also used as a reagent in the preparation of anti-angiogenic pyrroloazaflavones.

Synthesis Reference(s)

Tetrahedron Letters, 40, p. 5395, 1999 DOI: 10.1016/S0040-4039(99)01014-X

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