MEPHETYL TETRAZOLE
MEPHETYL TETRAZOLE Basic information
- Product Name:
- MEPHETYL TETRAZOLE
- Synonyms:
-
- MEPHETYL TETRAZOLE
- 1-[2-(4-Methoxyphenyl)ethyl]-5-(1-p-tolylcyclopropyl)-1H-tetrazole
- 1H-Tetrazole, 1-[2-(4-methoxyphenyl)ethyl]-5-[1-(4-methylphenyl)cyclopropyl]-
- CAS:
- 916923-10-9
- MF:
- C20H22N4O
- MW:
- 334.41
- Mol File:
- 916923-10-9.mol
More
Less
MEPHETYL TETRAZOLE Chemical Properties
- Boiling point:
- 558.4±39.0 °C(Predicted)
- Density
- 1.21±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMSO: >5mg/mL
- pka
- 1.11±0.10(Predicted)
- form
- oil
- color
- pale yellow
More
Less
Safety Information
- Safety Statements
- 22-24/25
- WGK Germany
- 3
More
Less
MEPHETYL TETRAZOLE Usage And Synthesis
Biological Activity
Mephetyl tetrazole is a potent and selective Kv1.5 potassium channel blocker. IC50 = 330 nM; shows selective atrial prolongation (40%) of effective refractory period (ERP), but no effect on ventricular ERP Kv1.5 channel is a molecular target for the treatment of atrial fibrillation.