Midesteine
Midesteine Basic information
- Product Name:
- Midesteine
- Synonyms:
-
- Midesteine
- MR 889
- N-[(Tetrahydro-2-oxothiophen)-3-yl]-2-[[(thiophen-2-yl)carbonyl]thio]propionamide
- 2-Thiophenecarbothioic acid, S-[1-methyl-2-oxo-2-[(tetrahydro-2-oxo-3-thienyl)amino]ethyl] ester
- CAS:
- 94149-41-4
- MF:
- C12H13NO3S3
- MW:
- 315.43
- Mol File:
- 94149-41-4.mol
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Midesteine Chemical Properties
- Boiling point:
- 559.3±50.0 °C(Predicted)
- Density
- 1.42±0.1 g/cm3(Predicted)
- pka
- 12.70±0.20(Predicted)
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Midesteine Usage And Synthesis
Uses
Midesteine (MR 889) is a proteinase inhibitor that can inhibit porcine pancreatic elastase, human neutrophil elastase and bovine chymotrypsin. Midesteine has the potential for chronic obstructive pulmonary disease (COPD) and chronic bronchitis research[1].
References
[1] M Luisetti, et al. Studies of MR 889, a new synthetic proteinase inhibitor. Biochem Biophys Res Commun. 1989 Dec 15;165(2):568-73. DOI:10.1016/s0006-291x(89)80004-x
[2] M Luisetti, et al. MR889, a neutrophil elastase inhibitor, in patients with chronic obstructive pulmonary disease: a double-blind, randomized, placebo-controlled clinical trial. Eur Respir J. 1996 Jul;9(7):1482-6. DOI:10.1183/09031936.96.09071482
MidesteineSupplier
TargetMol Chemicals Inc.
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Foshan Heshuo Pharm technology Co., ltd
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Shanghai Yifei Biotechnology Co. , Ltd.
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TargetMol Chemicals Inc.
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Shaanxi Xihua Chemical Industry Co., Ltd
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- 029-81136151 17392212881
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