Nafenopin Chemical Properties

Melting point:

117-118 °C

Boiling point:

390.55°C (rough estimate)

Density 

1.1662 (rough estimate)

refractive index 

1.4618 (estimate)

storage temp. 

Sealed in dry,Room Temperature

pka

3.28±0.10(Predicted)

IARC

2B (Vol. 24, Sup 7) 1987

EPA Substance Registry System

Nafenopin (3771-19-5)

Nafenopin Usage And Synthesis

Definition

ChEBI: A monocarboxylic acid that is 2-hydroxy-2-methylpropanoic acid in which ther tertiary hydroxy group has been converted to the corresponding p-(1,2,3,4-tetrahydronaphthalen-1-yl)phenyl ether.

General Description

Crystals.

Reactivity Profile

An organic acid. Carboxylic acids donate hydrogen ions if a base is present to accept them. They react in this way with all bases, both organic (for example, the amines) and inorganic. Their reactions with bases, called "neutralizations", are accompanied by the evolution of substantial amounts of heat. Neutralization between an acid and a base produces water plus a salt. Carboxylic acids in aqueous solution and liquid or molten carboxylic acids can react with active metals to form gaseous hydrogen and a metal salt. Such reactions occur in principle for solid carboxylic acids as well, but are slow if the solid acid remains dry. Even "insoluble" carboxylic acids may absorb enough water from the air and dissolve sufficiently in Nafenopin to corrode or dissolve iron, steel, and aluminum parts and containers. Carboxylic acids, like other acids, react with cyanide salts to generate gaseous hydrogen cyanide. The reaction is slower for dry, solid carboxylic acids. Insoluble carboxylic acids react with solutions of cyanides to cause the release of gaseous hydrogen cyanide. Flammable and/or toxic gases and heat are generated by the reaction of carboxylic acids with diazo compounds, dithiocarbamates, isocyanates, mercaptans, nitrides, and sulfides. Carboxylic acids, especially in aqueous solution, also react with sulfites, nitrites, thiosulfates (to give H2S and SO3), dithionites (SO2), to generate flammable and/or toxic gases and heat. Their reaction with carbonates and bicarbonates generates a harmless gas (carbon dioxide) but still heat. Like other organic compounds, carboxylic acids can be oxidized by strong oxidizing agents and reduced by strong reducing agents. These reactions generate heat. A wide variety of products is possible.

Fire Hazard

Flash point data for Nafenopin are not available. Nafenopin is probably combustible.

Safety Profile

Confirmed carcinogen with experimental carcinogenic and tumorigenic data. Moderately toxic by ingestion. Mutation data reported. A drug for the treatment of hypercholesterolemia or hypertriglyceridemia. When heated to decomposition it emits acrid smoke and irritating fumes.

Nafenopin(3771-19-5)Related Product Information

• 2-methyl-2-(4-methylphenoxy)propanoic acid
• AKOS B013930
• Nafenopin
• 2-(4-ISOPROPYLPHENOXY)PROPANOIC ACID
• 2-(4-ETHYLPHENOXY)PROPANOIC ACID
• 2-(4-ISOPROPYLPHENOXY)-2-METHYLPROPANOIC ACID