Terlakiren CAS#: 119625-78-4

Terlakiren Basic information

Product Name:

Terlakiren

Synonyms:

Terlakiren
CP 80794
(2R,3S)-4-Cyclohexyl-2-hydroxy-3-[(R)-3-methylthio-2-[(S)-2-(4-morpholinylcarbonylamino)-3-phenylpropanoylamino]propanoylamino]butyric acid isopropyl ester
L-Cysteinamide, N-(4-morpholinylcarbonyl)-L-phenylalanyl-N-[(1S,2R)-1-(cyclohexylmethyl)-2-hydroxy-3-(1-methylethoxy)-3-oxopropyl]-S-methyl-
ISOPROPYL (2R,3S)-4-CYCLOHEXYL-2-HYDROXY-3-[[(2R)-3-(METHYLSULFANYL)-2-([(2S)-2-[(4-MORPHOLINYLCARBONYL)AMINO]-3-PHENYLPROPANOYL]AMINO)PROPANOYL]AMINO]BUTANOATE

CAS:

119625-78-4

MF:

C31H48N4O7S

MW:

620.8

Mol File:

119625-78-4.mol

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Terlakiren Usage And Synthesis

Uses

Terlakiren (CP-80,794) is an orally active inhibitor of renin. Terlakiren inhibits the efficacy of human renin with an IC50 value of 0.7 nM. Terlakiren has potential applications in hypertension[1].

Definition

ChEBI: Terlakiren is a peptide.

References

[1] Fouda H, et al. Quantitative analysis by high-performance liquid chromatography atmospheric pressure chemical ionization mass spectrometry: The determination of the renin inhibitor CP-80,794 in human serum. J Am Soc Mass Spectrom. 1991 Apr;2(2):164-7. DOI:10.1016/1044-0305(91)80010-5

TerlakirenSupplier

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Shanghai Yifei Biotechnology Co. , Ltd.

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