Dactylfungin A Usage And Synthesis

Description

Dactylfungin A is isolated from Dactylaria parvispora. Dactylfungins are novel antifungal antibiotics produced by Dactylaria parvispora. Novel antifungal antibiotics, designated as dactylfungins A (1) and B (3), were isolated from the culture broth of Dactylaria parvispora D500. Dactylfungins A and B were found to be new substances containing an alpha-pyrone and a gamma-pyrone ring, respectively, which conjoined with a polyalcohol moiety and a long side chain, based on NMR spectral analyses. The antibiotics were active against Candida pseudotropicalis and other fungi, with an MIC value at less than 10 micrograms/ml.

Uses

Dactylfungin A, an α-pyrone-containing antifungal agent found in Dactylaria parvispora.

References

[1] Dactylfungins and Tetralones: Bioactive Metabolites from a Nematode-Associated Laburnicola nematophila

Dactylfungin A(146935-35-5)Related Product Information

• (Tetrahydro-pyran-2-yl)acetic acid
• ISOBUTYL ANGELATE
• METHYL 3-HYDROXY-2-METHYLENEBUTYRATE
• 4-HYDROXY-6-PROPYL-PYRAN-2-ONE
• Dactylfungin A