N-Biotinylaminoethyl Methanethiosulfonate
N-Biotinylaminoethyl Methanethiosulfonate Basic information
- Product Name:
- N-Biotinylaminoethyl Methanethiosulfonate
- Synonyms:
-
- N-Biotinylaminoethyl methylthiosulphonate
- Methanesulfonothioic Acid S-[2-[[5-[(3aS,4S,6aR)-Hexahydro-2-oxo-1H-thieno[3,4-d]iMidazol-4-yl]-1-oxopentyl]aMino]ethyl] Ester
- 2-[(Biotinoyl)-amino]-ethyl-methanthiosulfonat
- O-(2-(5-((3AS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)ethyl) methanesulfonothioate
- MTSEA-Biotin [N-Biotinoylaminoethyl methanethiosulfonate
- CAS:
- 162758-04-5
- MF:
- C13H23N3O4S3
- MW:
- 381.53
- Product Categories:
-
- Biotin Derivatives
- Cross Linking Reagents
- MTS & Sulfhydryl Active Reagents
- Mol File:
- 162758-04-5.mol
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N-Biotinylaminoethyl Methanethiosulfonate Chemical Properties
- Melting point:
- 95-103°C
- storage temp.
- -20°C Freezer, Under Inert Atmosphere
- solubility
- DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml
- form
- A crystalline solid
- Stability:
- Moisture Sensitive
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N-Biotinylaminoethyl Methanethiosulfonate Usage And Synthesis
Description
MTSEA-biotin is a thiol-reactive probe that can be used to label proteins at cysteine residues.
Chemical Properties
White Fluffy Solid
Uses
Reacts specifically and rapidly with thiols to form mixed disulfides. N-Biotinylaminoethyl Methanethiosulfonate can be used to probe the structures of the ACh receptor channel of the GABA receptor channel and of lactose permease. MTSEA-biotin has recently been used to probe the topology of the serotonin (5-HT) transporter by site-directed chemical labelling.
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