Aligeron
Aligeron Basic information
- Product Name:
- Aligeron
- Synonyms:
-
- Aligeron
- Piperazine, 1-(diphenylmethyl)-4-(2-propen-1-yl)-
- CAS:
- 70713-45-0
- MF:
- C20H24N2
- MW:
- 292.424
- Mol File:
- 70713-45-0.mol
Aligeron Chemical Properties
- Boiling point:
- 390.6±37.0 °C(Predicted)
- Density
- 1.044±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- pka
- 6.79±0.10(Predicted)
Aligeron Usage And Synthesis
Uses
Aligeron is a non-selective prostaglandin (PG) antagonist, and has vasodilatory properties.
in vivo
In hypoventilation hypoxia, aligeron (5 mg/kg i.v.) and cinnarizine increase cortical resistance to hypoxia and accelerated the recovery of cortical bioelectrical activity. In KCl- and AMP-induced depressions aligeron shows a protective effect manifested in a decrease of the degree and duration of the depression[2].
References
[1] Miyares K, et al. Antagonistic activity of aligeron and papaverine against different smooth muscle stimuli. Methods Find Exp Clin Pharmacol. 1985 Sep;7(9):473-6. PMID:4079597
[2] Dimov S, et al. Effect of aligeron and cinnarizine in models of general and local depression of the cortical bioelectrical activity in cats. Methods Find Exp Clin Pharmacol. 1983;5(2):89-95. PMID:6308367
AligeronSupplier
- Tel
- 1-631-485-4226; 16314854226
- info@bocsci.com
- Tel
- 15911056312
- liming@bio-fount.com
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
- Tel
- 021-51698675
- sales@jiejiegroup.com
- Tel
- 4008200310
- marketing@tsbiochem.com
Aligeron(70713-45-0)Related Product Information
- Flunarizine dihydrochloride
- Flunarizine
- Clocinizine
- Stugeron
- BW373U86 DIHYDROBROMIDE
- Aligeron
- SNC 80
- 4-[(AR*)-ALPHA-((2S*,5R*)-4-ALLYL-2,5-DIMETHYL-1-PIPERAZINYL)-3-HYDROXYBENZYL]-N,N-DIETHYLBENZAMIDE
- Trelnarizine
- 1-(4-(4-BENZHYDRYLPIPERAZIN-1-YL)-6-METHYL-1-PHENYL-2-THIOXO-1,2-DIHYDROPYRIMIDIN-5-YL)ETHANONE
- (E)-1-(4-BENZHYDRYLPIPERAZINO)-3-[4-(BENZYLOXY)PHENYL]-2-PROPEN-1-ONE
- 1,2-DIHYDRO-5-[[4-(DIPHENYLMETHYL)PIPERAZINO]CARBONYL]PYRROLO[3,2,1-IJ]QUINOLIN-4-ONE
- (E)-1-(4-BENZHYDRYLPIPERAZINO)-3-[4-(3-FLUOROPROPOXY)PHENYL]-2-PROPEN-1-ONE
- (E)-1-(4-BENZHYDRYLPIPERAZINO)-3-(2-METHOXYPHENYL)-2-PHENYL-2-PROPEN-1-ONE
- CLOCINIZINE DIHYDROCHLORIDE
- (E)-1-(4-BENZHYDRYLPIPERAZINO)-2-PHENYL-3-(2-THIENYL)-2-PROPEN-1-ONE
- (E)-1-(4-BENZHYDRYLPIPERAZINO)-3-(4-[(2,4-DICHLOROBENZYL)OXY]PHENYL)-2-PROPEN-1-ONE
- (E)-1-(4-BENZHYDRYLPIPERAZINO)-3-(4-[(4-BROMOBENZYL)OXY]PHENYL)-2-PROPEN-1-ONE