Butanixin
Butanixin Basic information
- Product Name:
- Butanixin
- Synonyms:
-
- 2-(p-Butylanilino)nicotinic acid
- 2-(4-butyl-anilino)-nicotinic acid
- 3-Pyridinecarboxylic acid, 2-[(4-butylphenyl)amino]-
- CAS:
- 55285-35-3
- MF:
- C16H18N2O2
- MW:
- 270.33
- Mol File:
- 55285-35-3.mol
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Butanixin Usage And Synthesis
Originator
Butanixin,ZYF Pharm Chemical
Manufacturing Process
5 g 2-chloronicotinic acid and 9.4 g p-n-butyl aniline were heated for 1 hour at 160°C by vigorous stirring under a nitrogen atmosphere. Then the mixture was dissolved in 2 N sodium hydroxide and extracted with benzene. The water layer was acidified and a precipitate obtained was filtered off, washed with water and dried. 5 g 2-[(4-butylphenyl)amino]-3-pyridinecarboxylic acid yielded. MP: 171°-173°C (deg.).
Therapeutic Function
Analgesic, Antiinflammatory