ethyl (E,4S)-4-[[(2R,5S)-2-[(4-fluorophenyl)methyl]-6-methyl-5-[(5-met hyloxazole-3-carbonyl)amino]-4-oxo-heptanoyl]amino]-5-[(3S)-2-oxopyrro lidin-3-yl]pent-2-enoate
ethyl (E,4S)-4-[[(2R,5S)-2-[(4-fluorophenyl)methyl]-6-methyl-5-[(5-met hyloxazole-3-carbonyl)amino]-4-oxo-heptanoyl]amino]-5-[(3S)-2-oxopyrro lidin-3-yl]pent-2-enoate Basic information
- Product Name:
- ethyl (E,4S)-4-[[(2R,5S)-2-[(4-fluorophenyl)methyl]-6-methyl-5-[(5-met hyloxazole-3-carbonyl)amino]-4-oxo-heptanoyl]amino]-5-[(3S)-2-oxopyrro lidin-3-yl]pent-2-enoate
- Synonyms:
-
- ethyl (E,4S)-4-[[(2R,5S)-2-[(4-fluorophenyl)methyl]-6-methyl-5-[(5-met hyloxazole-3-carbonyl)amino]-4-oxo-heptanoyl]amino]-5-[(3S)-2-oxopyrro lidin-3-yl]pent-2-enoate
- (2E,4S)-4-[[(2R,5S)-2-[(4-Fluorophenyl)methyl]-6-methyl-5-[[(5-methyl-3-isoxazolyl)carbonyl]amino]-1,4-dioxoheptyl]amino]-5-[(3S)-2-oxo-3-pyrrolidinyl]-2-pentenoic Acid
- AG 7088
- Rupintrivir
- 2-Pentenoicacid,4-[[(2R,5S)-2-[(4-fluorophenyl)methyl]-6-methyl-5-[[(5-methyl-3-isoxazolyl)carbonyl]amino]-1,4-dioxoheptyl]amino]-5-[(3S)-2-oxo-3-pyrrolidinyl]-, ethyl ester, (2E,4S)-
- Aids121840
- Aids-121840
- Ruprintrivir
- CAS:
- 223537-30-2
- MF:
- C31H39FN4O7
- MW:
- 598.66
- Product Categories:
-
- Chiral Reagents
- Heterocycles
- Anti-viral Compounds
- Anti-virals
- Intermediates & Fine Chemicals
- Isotope Labelled Compounds
- Pharmaceuticals
- Mol File:
- 223537-30-2.mol
More
Less
ethyl (E,4S)-4-[[(2R,5S)-2-[(4-fluorophenyl)methyl]-6-methyl-5-[(5-met hyloxazole-3-carbonyl)amino]-4-oxo-heptanoyl]amino]-5-[(3S)-2-oxopyrro lidin-3-yl]pent-2-enoate Chemical Properties
- Melting point:
- 170-171°C
- Boiling point:
- 866.7±65.0 °C(Predicted)
- Density
- 1.213
- storage temp.
- room temp
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- pka
- 12.16±0.46(Predicted)
- form
- powder
- color
- white to beige
- optical activity
- [α]/D +30 to +40°, c = 0.5 in chloroform-d
More
Less
ethyl (E,4S)-4-[[(2R,5S)-2-[(4-fluorophenyl)methyl]-6-methyl-5-[(5-met hyloxazole-3-carbonyl)amino]-4-oxo-heptanoyl]amino]-5-[(3S)-2-oxopyrro lidin-3-yl]pent-2-enoate Usage And Synthesis
Chemical Properties
White Solid
Uses
Labelled Rupintrivir. Rupintrivir (formerly AG7088) is an irreversible inhibitor of the human rhinovirus (HRV) 3C protease that has been demonstrated to have in vitro activity against all HRVs tested, consistent with its interaction with a strictly conserved subset of amino acids in the 3C protease.
General Description
Rupintrivir is an irreversible peptidomimetic inhibitor designed to target human rhinovirus (HRV). It was previously named as AG7088. It has been suggested that rupintrivir may be involved in vitro antiviral activity.
Biochem/physiol Actions
Rupintrivir (AG7088) is an irreversible human rhinovirus (HRV) 3C protease inhibitor, also found to inhibit enterovirus and norovirus.
ethyl (E,4S)-4-[[(2R,5S)-2-[(4-fluorophenyl)methyl]-6-methyl-5-[(5-met hyloxazole-3-carbonyl)amino]-4-oxo-heptanoyl]amino]-5-[(3S)-2-oxopyrro lidin-3-yl]pent-2-enoateSupplier
Wuhan Shanhai Zhihe Biotechnology Co., Ltd. Gold
- Tel
- 17771424646
- shoubull@126.com
J & K SCIENTIFIC LTD.
- Tel
- 010-82848833 400-666-7788
- jkinfo@jkchemical.com
Chemsky（shanghai）International Co.,Ltd.
- Tel
- 021-50135380
- shchemsky@sina.com
China Kouting Group Limited
- Tel
- +86 (21) 5811-6473 5811-6475
- sales@koutingchina.com
Credit Asia Chemical Co., Ltd.
- Tel
- +86 (21) 61124340