Basic information Safety Supplier Related

4-(2-METHYLAMINO-ETHYL)-PHENOL

Basic information Safety Supplier Related

4-(2-METHYLAMINO-ETHYL)-PHENOL Basic information

Product Name:
4-(2-METHYLAMINO-ETHYL)-PHENOL
Synonyms:
  • 2-(4-hydroxyphenyl)ethyl-methylammonium
  • methyl-4-tyramine
  • n-methyl-tyramin
  • p-(2-methylaminoethyl)-pheno
  • p-(2-methylaminoethyl)phenol
  • N-METHYL-P-TYRAMINE
  • 4-(2-METHYLAMINO-ETHYL)-PHENOL
  • 4-HYDROXY-N-METHYLPHENETHYLAMINE
CAS:
370-98-9
MF:
C9H13NO
MW:
151.21
EINECS:
206-731-3
Product Categories:
  • pharmacetical
Mol File:
370-98-9.mol
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4-(2-METHYLAMINO-ETHYL)-PHENOL Chemical Properties

Melting point:
130~131℃
Boiling point:
270.9±15.0 °C(Predicted)
Density 
1.035±0.06 g/cm3(Predicted)
storage temp. 
Refrigerator
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
9.86±0.15(Predicted)
color 
Pale Beige to Light Beige
InChI
InChI=1S/C9H13NO/c1-10-7-6-8-2-4-9(11)5-3-8/h2-5,10-11H,6-7H2,1H3
InChIKey
AXVZFRBSCNEKPQ-UHFFFAOYSA-N
SMILES
C1(O)=CC=C(CCNC)C=C1
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Safety Information

HS Code 
2922290090
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4-(2-METHYLAMINO-ETHYL)-PHENOL Usage And Synthesis

Uses

N-Methyltyramine is a protoalkaloid that can be isolated from various plant species. N-Methyltyramine is an α2-adrenoreceptor antagonist. N-Methyltyramine enhances appetite and digestion of foods by stimulating gastrin and pancreatic secretions. N-Methyltyramine can relax mouse small intestinal smooth muscle and inhibits small intestinal propulsion[1][2].

Definition

ChEBI: N-methyltyramine is a member of tyramines. It has a role as a mouse metabolite. It is a conjugate base of a N-methyltyraminium.

References

[1] Stohs SJ, et al. A review of the receptor binding and pharmacological effects of N-methyltyramine. Phytother Res. 2015 Jan;29(1):14-6. DOI:10.1002/ptr.5231
[2] Ni J, et al. Effect of N-methyltyramine on the regulation of adrenergic receptors via enzymatic epinephrine synthesis for the treatment of gastrointestinal disorders. Biomed Pharmacother. 2019 Mar;111:1393-1398. DOI:10.1016/j.biopha.2018.12.145

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