Basic information Safety Supplier Related

chloropeptide

Basic information Safety Supplier Related

chloropeptide Basic information

Product Name:
chloropeptide
Synonyms:
  • chloropeptide
  • CYCLOCHLOROTINE
  • ISLANDITOXIN
  • Cyclo[(3R)-3-phenyl-β-alanyl-L-seryl-(3S,4R)-3,4-dichloro-L-prolyl-(2S)-2-aminobutanoyl-L-seryl]
  • CCRIS 1316
CAS:
12663-46-6
MF:
C24H31Cl2N5O7
MW:
572.44
Mol File:
12663-46-6.mol
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chloropeptide Chemical Properties

Melting point:
255°C
Boiling point:
249°C (rough estimate)
Density 
1.5344 (rough estimate)
refractive index 
1.7350 (estimate)
pka
12.46±0.70(Predicted)
IARC
3 (Vol. 10, Sup 7) 1987
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Safety Information

Hazardous Substances Data
12663-46-6(Hazardous Substances Data)
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chloropeptide Usage And Synthesis

Uses

Cyclochlorotine is a mycotoxin that can be extracted from the yellow rice infectant Penicillium islandicum Sopp. Cyclochlorotine promotes glycogenolysis, inhibits glycogen synthesis, affects fat synthesis and protein synthesis in liver cells. Cyclochlorotine exhibits chronic toxicity in liver that induces liver fibrosis and cirrhosis in mouse models. Cyclochlorotine exhibits carcinogenicity[1].

References

[1] Uraguchi K, et al., Chronic toxicity and carcinogenicity in mice of the purified mycotoxins, luteoskyrin and cyclochlorotine. Food Cosmet Toxicol. 1972 Apr;10(2):193-207. DOI:10.1016/s0015-6264(72)80197-4

chloropeptideSupplier

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Nanjing Leon Biological Technology Co., Ltd.
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Nanjing Peptide Biotech Ltd.
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Zhejiang Huida Biotech Co., LTD
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