chloropeptide
chloropeptide Basic information
- Product Name:
- chloropeptide
- Synonyms:
-
- chloropeptide
- CYCLOCHLOROTINE
- ISLANDITOXIN
- Cyclo[(3R)-3-phenyl-β-alanyl-L-seryl-(3S,4R)-3,4-dichloro-L-prolyl-(2S)-2-aminobutanoyl-L-seryl]
- CCRIS 1316
- CAS:
- 12663-46-6
- MF:
- C24H31Cl2N5O7
- MW:
- 572.44
- Mol File:
- 12663-46-6.mol
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chloropeptide Chemical Properties
- Melting point:
- 255°C
- Boiling point:
- 249°C (rough estimate)
- Density
- 1.5344 (rough estimate)
- refractive index
- 1.7350 (estimate)
- pka
- 12.46±0.70(Predicted)
- IARC
- 3 (Vol. 10, Sup 7) 1987
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Safety Information
- Hazardous Substances Data
- 12663-46-6(Hazardous Substances Data)
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chloropeptide Usage And Synthesis
Uses
Cyclochlorotine is a mycotoxin that can be extracted from the yellow rice infectant Penicillium islandicum Sopp. Cyclochlorotine promotes glycogenolysis, inhibits glycogen synthesis, affects fat synthesis and protein synthesis in liver cells. Cyclochlorotine exhibits chronic toxicity in liver that induces liver fibrosis and cirrhosis in mouse models. Cyclochlorotine exhibits carcinogenicity[1].
References
[1] Uraguchi K, et al., Chronic toxicity and carcinogenicity in mice of the purified mycotoxins, luteoskyrin and cyclochlorotine. Food Cosmet Toxicol. 1972 Apr;10(2):193-207. DOI:10.1016/s0015-6264(72)80197-4
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chloropeptide(12663-46-6)Related Product Information
- chloropeptide
- (R)-3-AMINO-2(BENZYLAMINO)PROPAN-1-OL
- 2-CHLORO-N,N-DIETHYLPROPANAMINE HYDROCHLORIDE
- 3-CHLORO-N-ISOPROPYLPROPANAMIDE
- 1-DIETHYLAMINO-2-CHLOROPROPANE
- 1-CHLORO-N,N-DIMETHYL-2-PROPYLAMINE
- PYRROLIDINE, 3-CHLORO-, HYDROCHLORIDE
- 3-DIETHYLAMINOPROPYL CHLORIDE HYDROCHLORIDE
- (R)-N-(2-PROPYL)-1-PHENYLETHYLAMINE HYDROCHLORIDE
- N,N'-Bis(2-Hydroxyethyl)propane-1,3-diamine