5-(carboxymethylaminomethyl)-2-thiouridine
5-(carboxymethylaminomethyl)-2-thiouridine Basic information
- Product Name:
- 5-(carboxymethylaminomethyl)-2-thiouridine
- Synonyms:
-
- 5-(carboxymethylaminomethyl)-2-thiouridine
- Glycine, N-[(1,2,3,4-tetrahydro-4-oxo-1-β-D-ribofuranosyl-2-thioxo-5-pyrimidinyl)methyl]-
- CAS:
- 78173-95-2
- MF:
- C12H17N3O7S
- MW:
- 347.34
- Mol File:
- 78173-95-2.mol
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5-(carboxymethylaminomethyl)-2-thiouridine Chemical Properties
- Density
- 1.72±0.1 g/cm3(Predicted)
- pka
- 2.20±0.10(Predicted)
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5-(carboxymethylaminomethyl)-2-thiouridine Usage And Synthesis
Uses
5-Carboxymethylaminomethyl-2-thiouridine or mcm5S2U, is a naturally occurring 2-thio-modification of tRNA catalyzed by the action of Nfs1 enzyme on cy-tRNALyS2UUU and cy-tRNAGlU3UUC
Definition
ChEBI: A thiouridine that is 2-thiouridine bearing an additional carboxymethylaminomethyl substituent at position 5 on the thiouracil ring.