11β-Hydroxyandrost-4-ene-3,17-dione Chemical Properties

Melting point:

197-199℃

Boiling point:

475.3±45.0 °C(Predicted)

Density 

1.19±0.1 g/cm3(Predicted)

storage temp. 

Store at -20°C

solubility 

DMSO: 250 mg/mL (826.69 mM)

form 

A crystalline solid

pka

14.49±0.60(Predicted)

color 

White to off-white

InChI

InChI=1S/C19H26O3/c1-18-8-7-12(20)9-11(18)3-4-13-14-5-6-16(22)19(14,2)10-15(21)17(13)18/h9,13-15,17,21H,3-8,10H2,1-2H3/t13-,14-,15-,17+,18-,19-/m0/s1

InChIKey

WSCUHXPGYUMQEX-KCZNZURUSA-N

SMILES

C1[C@@]2(C)C(CC[C@]3([H])[C@]2([H])[C@@H](O)C[C@@]2(C)[C@@]3([H])CCC2=O)=CC(=O)C1

Safety Information

WGK Germany 

3

MSDS

• Language:English Provider:SigmaAldrich

11β-Hydroxyandrost-4-ene-3,17-dione Usage And Synthesis

Uses

4-Androsten-11β-ol-3,17-dione is a steroid hormone. An analog of Androstenedione (A637550).

Definition

ChEBI: 11beta-hydroxyandrost-4-ene-3,17-dione is an 11beta-hydroxy steroid, a 3-oxo steroid, a 17-oxo steroid and an androstanoid. It has a role as a human metabolite and a mouse metabolite.

Biochem/physiol Actions

11β-Hydroxy-4-androstene-3,17-dione is a naturally occurring steroid that is primarily, if not strictly, produced in adrenal tissue. In diseases such as Cushing′s syndrome, adrenal-originated hyperandrogenism, and congenital adrenal hyperplasia, plasma 11β levels are very high. Plasma 11β concentration is very low in congenital 11-hydroxylase deficiency and adrenal insufficiency.

in vivo

IC 50

Human Endogenous Metabolite

11β-Hydroxyandrost-4-ene-3,17-dione(382-44-5)Related Product Information

• 5-ANDROSTEN-11-BETA-OL-3,17-DIONE DIETHYLENEKETAL
• 11BETA-HYDROXYANDROSTENDIONE-3-O-CMO
• 4-ANDROSTEN-11BETA-OL-3,17-DIONE-2,2,4,6,6,16,16-D7
• 11β-Hydroxyandrost-4-ene-3,17-dione
• CYCLOTRIDECANONE
• TETRAHYDROJASMONE
• 5-ANDROSTENEDIOL
• CYCLONONANONE
• 3-CYCLOPENTYL-1-PROPANOL
• 3-Methylcyclopentanone