1,4-DIHYDRO-2-METHYL-6-PHENYL-4-(PHENYLETHYNYL)-3,5-PYRIDINEDICARBOXYLIC ACID 3-ETHYL-5-[(3-NITROPHENYL)METHYL] ESTER Chemical Properties

Boiling point:

704.2±60.0 °C(Predicted)

Density 

1.31±0.1 g/cm3(Predicted)

storage temp. 

Desiccate at -20°C

solubility 

Soluble to 100 mM in DMSO

form 

Powder

pka

1.46±0.70(Predicted)

color 

White to off-white

1,4-DIHYDRO-2-METHYL-6-PHENYL-4-(PHENYLETHYNYL)-3,5-PYRIDINEDICARBOXYLIC ACID 3-ETHYL-5-[(3-NITROPHENYL)METHYL] ESTER Usage And Synthesis

Uses

MRS 1334 is a potent and highly selective hA3 antagonist.

Definition

ChEBI: 2-methyl-6-phenyl-4-(2-phenylethynyl)-1,4-dihydropyridine-3,5-dicarboxylic acid O3-ethyl ester O5-[(4-nitrophenyl)methyl] ester is a cinnamate ester.

Biological Activity

Potent and highly selective antagonist for the human adenosine A 3 receptor. K i values are 2.69 nM at hA 3 , and > 100 μ M at rat A 1 and rat A 2A receptors.

storage

Desiccate at -20°C

1,4-DIHYDRO-2-METHYL-6-PHENYL-4-(PHENYLETHYNYL)-3,5-PYRIDINEDICARBOXYLIC ACID 3-ETHYL-5-[(3-NITROPHENYL)METHYL] ESTER(192053-05-7)Related Product Information

• 4-Fluorocinnamic acid
• 5-PHENYL-4-PENTYN-1-OL
• 1,4-DIHYDRO-2-METHYL-6-PHENYL-4-(PHENYLETHYNYL)-3,5-PYRIDINEDICARBOXYLIC ACID 3-ETHYL-5-[(3-NITROPHENYL)METHYL] ESTER