aspalatone Chemical Properties

storage temp. 

Store at -20°C

solubility 

DMF: 10 mg/ml; DMSO: 10 mg/ml; DMSO:PBS (pH 7.2) (1:10): 0.1 mg/ml; Ethanol: 1 mg/ml

form 

A crystalline solid

aspalatone Usage And Synthesis

Uses

Aspalatone is an orally active antiplatelet aggregant with IC50 of 180 μM. Aspalatone has antioxidant and neuroprotective activities[1][2].

References

[1] Han BH, et al. Synthesis and antiplatelet effects of the new antithrombotic agent aspalatone with low ulcerogenicity. Arzneimittelforschung. 1994 Oct;44(10):1122-6. PMID:7818584
[2] Kim HC, et al. Aspalatone, a new antiplatelet agent, attenuates the neurotoxicity induced by kainic acid in the rat. Life Sci. 1997;61(24):PL 373-81. DOI:10.1016/s0024-3205(97)00963-6

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