4,4-dimethyl-5-alpha-cholesta-(8,24)-dien-3-beta-ol
4,4-dimethyl-5-alpha-cholesta-(8,24)-dien-3-beta-ol Basic information
- Product Name:
- 4,4-dimethyl-5-alpha-cholesta-(8,24)-dien-3-beta-ol
- Synonyms:
-
- 4,4-dimethyl-5-alpha-cholesta-(8,24)-dien-3-beta-ol
- 30-Nor-8,24-lanostadiene-3β-ol
- 30-Norlanosta-8,24-dien-3β-ol
- 30-Norlanosterol
- 4,4-Dimethyl-5α-cholesta-8,24-dien-3β-ol
- 4,4-Dimethylzymosterol
- Norlanosterol
- Cholesta-8,24-dien-3-ol,4,4-diMethyl-, (3b,5a)-
- CAS:
- 7448-02-4
- MF:
- C29H48O
- MW:
- 412.69
- Mol File:
- 7448-02-4.mol
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4,4-dimethyl-5-alpha-cholesta-(8,24)-dien-3-beta-ol Chemical Properties
- storage temp.
- -70°C
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4,4-dimethyl-5-alpha-cholesta-(8,24)-dien-3-beta-ol Usage And Synthesis
Uses
14-Norlanosterol, is a metabolite of Lanosterol (L174580). It is also a meiosis activating sterol (MAS), which is shown to have an important role in regulating meiosis and reproduction.
Uses
14-demethyl-lanosterol has been used to reduce cancer cell viability and increase cancer cell sensitivity to erlotinib.
Definition
ChEBI: A 3beta-sterol formed formally by loss of a methyl group from the 14-position of lanosterol.
General Description
14-demethyl-lanosterol acts as an intermediate in cholesterol biosynthesis. It is used to stimulate oocytes for meiosis. 14-demethyl-lanosterol modulates cumulus expansion.
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