1-(8-CHLORO-10,11-DIHYDRODIBENZO[B,F]THIEPIN-10-YL)-4-METHYL-PIPERAZINE MALEATE
1-(8-CHLORO-10,11-DIHYDRODIBENZO[B,F]THIEPIN-10-YL)-4-METHYL-PIPERAZINE MALEATE Basic information
- Product Name:
- 1-(8-CHLORO-10,11-DIHYDRODIBENZO[B,F]THIEPIN-10-YL)-4-METHYL-PIPERAZINE MALEATE
- Synonyms:
-
- 1-(8-chloro-10,11-dihydrodibenzo(b,f)thiepin-10-yl)-4-methyl-piperazinmale
- 8-chloro-10-(4-methylpiperazino)-10,11-dihydrodibenzo(b,f)thiepinmaleate
- d,l-8-chloro-10-(4-methylpiperazino)-10,11-dihydrodibenzo(b,f)thiepinmaleate
- octoclothepinemaleate
- vufb-6281
- OCTOCLOTHEPIN MALEATE
- OCTOCLOTHEPIN MALEATE SALT
- 1-(8-CHLORO-10,11-DIHYDRODIBENZO[B,F]THIEPIN-10-YL)-4-METHYL-PIPERAZINE MALEATE
- CAS:
- 4789-68-8
- MF:
- C23H25ClN2O4S
- MW:
- 460.97
- Mol File:
- 4789-68-8.mol
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1-(8-CHLORO-10,11-DIHYDRODIBENZO[B,F]THIEPIN-10-YL)-4-METHYL-PIPERAZINE MALEATE Chemical Properties
- solubility
- 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: >21 mg/mL
- form
- solid
- color
- white
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Safety Information
- Hazard Codes
- T
- Risk Statements
- 25
- Safety Statements
- 36/37/39-45
- RIDADR
- UN 2811 6.1/PG 3
- WGK Germany
- 3
- RTECS
- TL1575000
MSDS
- Language:English Provider:SigmaAldrich
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1-(8-CHLORO-10,11-DIHYDRODIBENZO[B,F]THIEPIN-10-YL)-4-METHYL-PIPERAZINE MALEATE Usage And Synthesis
Uses
Octoclothepin Maleate Salt is an SR-2A inhibitor as well as a D2DR inhibitor.
Biological Activity
D2 dopamine receptor antagonist; 5-HT2 serotonin receptor antagonist.
in vivo
Octoclothepin possesses high cataleptogenic and anti-apomorphine activities in rats; it is able to exert full protection against apomorphine-induced emesis in dogs after the dose of 0.1 mg/kg s.c.[1].
Octoclothepin in doses of 0.5 and 1.5 mg/kg s.c. reduces the DA level and raises the HVA and DOPAC levels significantly[1].
1-(8-CHLORO-10,11-DIHYDRODIBENZO[B,F]THIEPIN-10-YL)-4-METHYL-PIPERAZINE MALEATESupplier
Energy Chemical
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- 021-58432009 400-005-6266
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- 15002134094
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TargetMol Chemicals Inc.
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1-(8-CHLORO-10,11-DIHYDRODIBENZO[B,F]THIEPIN-10-YL)-4-METHYL-PIPERAZINE MALEATE(4789-68-8)Related Product Information
- 2-Chloro-11-(4-(2-mandeloyloxyethyl)piperazino)-10,11-dihydrodibenzo(b ,f)thiepin bis(maleate)
- 4-(8-Chloro-10,11-dihydrodibenzo(b,f)thiepin-10-yl)-1-piperazinebutano l dimaleate
- 1-(8-CHLORO-10,11-DIHYDRODIBENZO[B,F]THIEPIN-10-YL)-4-METHYL-PIPERAZINE MALEATE
- 1-Piperazinebutanol, 4-(8-chloro-10,11-dihydrodibenzo(b,f)thiepin-10-y l)-alpha-methyl-, (Z)-2-butenedioate (1:2)
- Piperazine, 1-(8-chloro-10,11-dihydrodibenzo(b,f)thiepin-10-yl)-4-meth yl-, S-oxide, (Z)-2-butenedioate (1:1)