4-(1-Phenyl-1H-benzimidazol-2-yl)phenylboronic acid Chemical Properties

Boiling point:

572.6±60.0 °C(Predicted)

Density 

1.21±0.1 g/cm3(Predicted)

storage temp. 

under inert gas (nitrogen or Argon) at 2-8°C

solubility 

soluble in Methanol

form 

powder to crystal

pka

8.47±0.17(Predicted)

color 

White to Light yellow to Light orange

Safety Information

HS Code 

2933.99.9701

4-(1-Phenyl-1H-benzimidazol-2-yl)phenylboronic acid Usage And Synthesis

Chemical Properties

White to off-white powder

Synthesis

The 7g 2 - (4-bromophenyl) - 1-phenyl-benzimidazole (0.02mole) adding 150mlTHF in, lower the temperature to -78 °C, at -78 ° C dropping under 12 ml (2.5M/L, 0 . 03mole) n-BuLi, thermal insulation 30 minutes, dropping 4.26g (0.041mole) methyl borate, reaction 2 hours after the reaction end of the water in the reaction solution of 50 ml, stirring 20 minutes, hydrochloric acid to adjust pH value to acidity, stirring 30 minutes, the reaction solution with ethyl acetate extraction three times, washing time combined with the organic layer, the organic phase is separated, turns on lathe does, solid with petroleum ether heat two times, filtering, to obtain solid intermediates kind of white 4-(1-Phenyl-1H-benzimidazol-2-yl)phenylboronic acid, yield 65percent.

4-(1-Phenyl-1H-benzimidazol-2-yl)phenylboronic acid(952514-79-3)Related Product Information

• 4-(1-Phenyl-1H-benzimidazol-2-yl)phenylboronic acid
• 1,2-Diphenyl-1H-benzimidazole