4-AMINO-2-MERCAPTOPYRIMIDINE Chemical Properties

Melting point:

285-290 °C (dec.)(lit.)

Boiling point:

232.1±43.0 °C(Predicted)

Density 

1.313 (estimate)

refractive index 

1.5800 (estimate)

storage temp. 

-20°C Freezer

solubility 

DMSO (Slightly), Water (Slightly)

form 

Powder

pka

7.91±0.10(Predicted)

color 

Yellow

BRN 

112435

CAS DataBase Reference

333-49-3(CAS DataBase Reference)

EPA Substance Registry System

2(1H)-Pyrimidinethione, 4-amino- (333-49-3)

Safety Information

Safety Statements 

22-24/25

WGK Germany 

3

RTECS 

UW0520000

HS Code 

29335995

MSDS

• Language:English Provider:SigmaAldrich

4-AMINO-2-MERCAPTOPYRIMIDINE Usage And Synthesis

Chemical Properties

Beige toYellow Powder

Uses

This compound has been shown to inhibit iodothyronine 5’-deiodinase, the enzyme responsible for the 5’-deiodination of thyroxine in human liver cells.

Uses

2-Thiocytosine has been used to investigate the reactions involved in hole transfer (HT) in X-irradiated doped cytosine monohydrate.

General Description

2-Thiocytosine is a potential antileukemic and anticancer agent. 2-Thiocytosine in solid state has been investigated by (1)H-(14)N NMR-NQR double resonance (NQDR) spectroscopy and theoretically by the quantum theory of atoms in molecules (QTAIM)/density functional theory (DFT).

Purification Methods

It is recrystallised from hot H2O and dried at 100o to constant weight. [Brown J Appl Chem (London) 9 203 1959, Russell et al. J Am Chem Soc 71 2279 1949.] It is used in transcription and translation studies [Rachwitz & Scheit Eur J Biochem 72 191 1977].

4-AMINO-2-MERCAPTOPYRIMIDINE(333-49-3)Related Product Information

• 4-AMINO-2-(METHYLTHIO)PYRIMIDINE-5-CARBONITRILE
• Ethyl 4-amino-2-(ethylthio)-5-pyrimidinecarboxylate
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• 4-AMINO-2-MERCAPTOPYRIMIDINE
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• 4,5-DIAMINO-2-MERCAPTOPYRIMIDINE
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• 2-THIOCYTIDINE
• 2,4-DIAMINO-6-MERCAPTOPYRIMIDINE HEMISULFATE
• 4-Amino-2-mercaptopyrimidine-5-carbonitrile ,97%
• 4,5-DIAMINO-6-MERCAPTOPYRIMIDINE
• 2,4-DIAMINO-6-MERCAPTOPYRIMIDINE