VANDETANIB
VANDETANIB Basic information
- Product Name:
- VANDETANIB
- Synonyms:
-
- (4-BROMO-2-FLUORO-PHENYL)-[6-METHOXY-7-(1-METHYL-PIPERIDIN-4-YLMETHOXY)-QUINAZOLIN-4-YL]-AMINE
- VANDETANIB FUMARATE
- HSDB 8198
- CAS:
- 338992-00-0
- MF:
- C22H24BrFN4O2
- MW:
- 0
- Mol File:
- 338992-00-0.mol
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VANDETANIB Usage And Synthesis
Uses
Treatment of non-small cell lung cancer and other solid tumors.
Definition
ChEBI: Vandetanib is a quinazoline that is 7-[(1-methylpiperidin-4-yl)methoxy]quinazoline bearing additional methoxy and 4-bromo-2-fluorophenylamino substituents at positions 6 and 4 respectively. Used for the treatment of symptomatic or progressive medullary thyroid cancer in patients with unresectable locally advanced or metastatic disease. It has a role as a tyrosine kinase inhibitor and an antineoplastic agent. It is an aromatic ether, a secondary amine, a member of quinazolines, a member of piperidines, an organobromine compound and an organofluorine compound.
brand name
Zactima (AstraZeneca).
VANDETANIBSupplier
Alfa Chemistry
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AFINE CHEMICALS LIMITED
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TargetMol Chemicals Inc.
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