Basic information Safety Supplier Related

(6R)-Hydroxy (S,S)-Palonosetron

Basic information Safety Supplier Related

(6R)-Hydroxy (S,S)-Palonosetron Basic information

Product Name:
(6R)-Hydroxy (S,S)-Palonosetron
Synonyms:
  • (6R)-Hydroxy (S,S)-Palonosetron
  • (3aS,6R)-2-[(3S)-1-azabicyclo[2.2.2]octan-3-yl]-6-hydroxy-3a,4,5,6-tetrahydro-3H-benzo[de]isoquinolin-1-one
  • (6R)-Hydroxy Palonosetron
  • 1H-Benz[de]isoquinolin-1-one, 2-(1-azabicyclo[2.2.2]oct-3-yl)-2,3,3a,4,5,6-hexahydro-6-hydroxy-, [3aS-[2(R*),3aα,6β]]- (9CI)
  • Palonosetron Impurity 47
  • Palonosetron Impurity 28
  • Aurofusarin Impurity 14
CAS:
176019-33-3
MF:
C19H24N2O2
MW:
312.41
Mol File:
176019-33-3.mol
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(6R)-Hydroxy (S,S)-Palonosetron Chemical Properties

Boiling point:
515.4±50.0 °C(Predicted)
Density 
1.32±0.1 g/cm3(Predicted)
pka
14.32±0.20(Predicted)
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(6R)-Hydroxy (S,S)-Palonosetron Usage And Synthesis

Uses

(6R)-Hydroxy (S,S)-Palonosetron is a stereoisomer of (6S)-Hydroxy (S,S)-Palonosetron (H949365). (6S)-Hydroxy (S,S)-Palonosetron (H949365) is a metabolite of Palonosetron (P165800, HCl salt) which is a potent, single stereoisomeric 5-HT3 receptor antagonist developed to prevent chemotherapy-induced nausea and vomiting.

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