5-AMino-2-chloropyriMidine-4-carboxaMide Chemical Properties

Boiling point:

452.3±25.0 °C(Predicted)

Density 

1.585±0.06 g/cm3(Predicted)

pka

13.22±0.50(Predicted)

5-AMino-2-chloropyriMidine-4-carboxaMide Usage And Synthesis

Uses

5-Amino-2-chloropyrimidine-4-carboxamide is a building block related to Favipiravir(F103350). Favipiravir is used for the treatment of advanced Ebola virus infection in a small animal model. Favipiravir suppressed the replication of Zaire Ebola virus and prevented a lethal outcome in 100% of the animals. Based on the studies, Favipiravir can be a candidate for the treatment of Ebola hemorrhagic fever.