KINETENSIN Chemical Properties

storage temp. 

2-8°C

solubility 

TFA 0.1%: 1 mg/mL, clear, colorless

form 

Powder

color 

White to off-white

Water Solubility 

Soluble to 2 mg/ml in water

Sequence

Ile-Ala-Arg-Arg-His-Pro-Tyr-Phe-Leu

Safety Information

Safety Statements 

22-24/25

WGK Germany 

3

F 

10

MSDS

• Language:English Provider:SigmaAldrich

KINETENSIN Usage And Synthesis

Uses

Kinetensin is a neurotensin-like peptide isolated from pepsin-treated human plasma.

Definition

ChEBI: Kinetensin is an oligopeptide comprising of nine amino acids with sequence L-Ile-L-Ala-L-Arg-L-Arg-L-His-L-Pro-L-Tyr-L-Phe-L-Leu. It was originally isolated from pepsin-treated human plasma and shares some sequence homology with the C-terminal end of neurotensin. It is a potent histamine releaser and may serve as an inflammatory mediator. It has a role as a human metabolite and a histamine releasing agent. It is a conjugate base of a kinetensin(2+).

in vivo

IC 50

Human Endogenous Metabolite

References

[1] Mogard MH, et al. The amino acid sequence of kinetensin, a novel peptide isolated from pepsin-treated human plasma: homology with human serum albumin, neurotensin and angiotensin. Biochem Biophys Res Commun. 1986 May 14;136(3):983-8. DOI:10.1016/0006-291x(86)90429-8
[2] Sydbom A, et al. Stimulation of histamine release by the peptide kinetensin. Agents Actions. 1989 Apr;27(1-2):68-71. DOI:10.1007/BF02222201

KINETENSIN(103131-69-7)Related Product Information

• (DES-LEU9)-KINETENSIN
• (DES-TYR1)-LEU-ENKEPHALIN
• KINETENSIN