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Ozanimod hydrochloride

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Ozanimod hydrochloride Basic information

Product Name:
Ozanimod hydrochloride
Synonyms:
  • Ozanimod hydrochloride
  • Ozanimod hydrochloride Impurity 1
  • (S)-4-(5-(3-cyano-4-isopropoxyphenyl)-1,2,4-oxadiazol-3-yl)-N-(2-hydroxyethyl)-2,3-dihydro-1H-inden-1-aminium chloride
  • Ozanimod hyd
  • (S)-5-(3-(1-((2-Hydroxyethyl)amino)-2,3-dihydro-1H-inden-4-yl)-1,2,4-oxadiazol-5-yl)-2-isopropoxybenzonitrile hydrochloride
CAS:
1618636-37-5
MF:
C23H25ClN4O3
MW:
440.93
Mol File:
1618636-37-5.mol
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Ozanimod hydrochloride Chemical Properties

form 
Solid
color 
White to off-white
InChIKey
HAOOCAKHSFYDBU-OZYVVJTJNA-N
SMILES
N([C@H]1CCC2=C(C3=NOC(C4C=CC(OC(C)C)=C(C#N)C=4)=N3)C=CC=C12)CCO.Cl |&1:1,r|
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Ozanimod hydrochloride Usage And Synthesis

Description

Ozanimod hydrochloride (RPC-1063 hydrochloride) is an orally available, selective and potent sphingosine 1-phosphate (S1P) receptor modulator that shows high affinity for S1P1 and S1P5. Ozanimod has potential anticancer activity and can be used in studying multiple sclerosis (MS), ulcerative multiple sclerosis (UMS), and other diseases. (MS), ulcerative colitis, coronavirus infections and myelodysplasia.

Chemical Properties

Ozanimod hydrochloride is a white to off-white solid with a melting point of ~240°C. It is poorly hygroscopic. The solubility of ozanimod hydrochloride in ethanol and methanol is 1.43 and 2.41 mg/mL; in a pH 5.1, aqueous medium is 3.51 mg/mL. The pKa for this compound is 7.90, and the partition coefficient (logP) is 3.28.

Ozanimod hydrochlorideSupplier

Shijiazhuang Dingmin pharmaceutical Sciences Co.,Ltd Gold
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0311-67591193 15030197620
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SHANGHAI YINGRUI CHEMICAL TECHNOLOGY CO.,LTD.
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021-34666753 13311639313
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info@shyrchem.com
Taizhou Tongxin Bio-Tech Co., Ltd
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0523-18601685-898 18652728585
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sales@allyrise.com
Chengdu Miracle Pharmaceutical Co., Ltd.
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028-86136736 19130631884
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Taizhou Ruixin Chemical Co., Ltd.
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0576-89085261 15867635987
Email
jasonhu09@163.com
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Ozanimod hydrochloride(1618636-37-5)Related Product Information