Basic information Safety Supplier Related

O6-METHYL-2'-DEOXYGUANOSINE

Basic information Safety Supplier Related

O6-METHYL-2'-DEOXYGUANOSINE Basic information

Product Name:
O6-METHYL-2'-DEOXYGUANOSINE
Synonyms:
  • 6-O-METHYL-2'-DEOXYGUANOSINE
  • O6-METHYL-2'-DEOXYGUANOSINE
  • 2-Amino-6-methoxy-2'-deoxy-6-deaminoadenosine
  • 9-(2-Deoxy-β-D-ribofuranosyl)-6-methoxy-9H-purin-2-amine
  • (2R,3S,5R)-5-(2-amino-6-methoxypurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol
  • (2R,3S,5R)-5-(2-amino-6-methoxy-purin-9-yl)-2-methylol-tetrahydrofuran-3-ol
  • (2R,3S,5R)-5-(2-azanyl-6-methoxy-purin-9-yl)-2-(hydroxymethyl)oxolan-3-ol
  • 2-amino-9-(2-deoxy-β-D-erythro-pentofuranosyl)-6-methoxypurine
CAS:
964-21-6
MF:
C11H15N5O4
MW:
281.27
Mol File:
964-21-6.mol
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O6-METHYL-2'-DEOXYGUANOSINE Chemical Properties

Melting point:
109 - 115°C
Boiling point:
674.7±65.0 °C(Predicted)
Density 
1.84±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Aqueous Base (Slightly, Sonicated), DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
13.76±0.60(Predicted)
color 
White to Off-White
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O6-METHYL-2'-DEOXYGUANOSINE Usage And Synthesis

Uses

O6-Methyl-2’-deoxyguanosine is a ubiquitous DNA lesion formed by xenobiotic carcinogens and endogenous methylating agent, S-adenosyl-L-methionine. A mutagenic adducts formed by a potent tobacco carcinogen, 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).

Definition

ChEBI: A purine 2'-deoxyribonucleoside having O6-methylguanine as the nucleobase.

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