4',5'-Didehydro-2'-O-(2-methoxyethyl)-5-methyluridine Chemical Properties

Density 

1.35±0.1 g/cm3(Predicted)

pka

9.50±0.10(Predicted)

4',5'-Didehydro-2'-O-(2-methoxyethyl)-5-methyluridine Usage And Synthesis

Uses

4’,5’-Didehydro-2’-O-(2-methoxyethyl)-5-methyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

References

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005

4',5'-Didehydro-2'-O-(2-methoxyethyl)-5-methyluridine(2095417-31-3)Related Product Information

• 4',5'-Didehydro-2'-O-methyl-5-methyluridine
• 4',5'-Didehydro-5'-deoxythymidine
• 4',5'-Didehydro-5'-deoxy-5-methyluridine
• 4',5'-Didehydro-5'-deoxy-2'-O-methyluridine
• Uridine, 4',5'-didehydro-5'-deoxy-