KDM4D-IN-1
KDM4D-IN-1 Basic information
- Product Name:
- KDM4D-IN-1
- Synonyms:
-
- KDM4D-IN-1
- KDM4D-IN-10r
- KDM4D inhibitor 1
- KDM4D-IN-1, >98%
- Pyrazolo[1,5-a]pyrido[3,2-e]pyrimidine-3-carbonitrile, 4,5-dihydro-2-methyl-5-oxo-
- KDM4DIN1,Histone Demethylase,KDM4D IN 1,Inhibitor,KDM-4D-IN-1,inhibit
- 2-Methyl-5-oxo-4,5-dihydropyrazolo[1,5-a]pyrido[3,2-e]pyrimidine-3-carbonitrile
- KDM4D-IN-1, 10 mM in DMSO
- CAS:
- 2098902-68-0
- MF:
- C11H7N5O
- MW:
- 225.21
- Mol File:
- 2098902-68-0.mol
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KDM4D-IN-1 Chemical Properties
- Boiling point:
- 366.2±42.0 °C(Predicted)
- Density
- 1.58±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO : 6 mg/mL (26.64 mM)
- form
- Solid
- pka
- 10.33±0.20(Predicted)
- color
- Light yellow to khaki
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KDM4D-IN-1 Usage And Synthesis
Uses
KDM4D-IN-1 is a new histone lysine demethylase 4D (KDM4D) inhibitor with an IC50 value of 0.41±0.03 μM.
IC 50
KDM4
References
[1] Fang Z, et al. Discovery of pyrazolo[1,5-a]pyrimidine-3-carbonitrile derivatives as a new class of histone lysine demethylase 4D (KDM4D) inhibitors. Bioorg Med Chem Lett. 2017 Jul 15;27(14):3201-3204. DOI:10.1016/j.bmcl.2017.05.002
KDM4D-IN-1Supplier
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