CB-1158
CB-1158 Basic information
- Product Name:
- CB-1158
- Synonyms:
-
- (3R,4S)-1-(L-alanyl)-3-amino-4-(3-boronopropyl)pyrrolidine-3-carboxylic acid
- INCB01158
- 3-Pyrrolidinecarboxylic acid, 3-amino-1-[(2S)-2-amino-1-oxopropyl]-4-(3-boronopropyl)-, (3R,4S)-
- Numidargistat (CB1158, INCB01158)
- Numidargistat 2HCl (CB1158, INCB01158)
- Numidargistat
- (3R,4S)-3-Amino-1-[(2S)-2-aminopropanoyl]-4-[3-(dihydroxyboranyl)propyl]pyrrolidine-3-carboxylic acid
- CAS:
- 2095732-06-0
- MF:
- C11H22BN3O5
- MW:
- 287.12
- Product Categories:
-
- pyrolidine
- Mol File:
- 2095732-06-0.mol
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CB-1158 Chemical Properties
- Boiling point:
- 574.1±60.0 °C(Predicted)
- Density
- 1.299±0.06 g/cm3(Predicted)
- pka
- 2.13±0.40(Predicted)
- form
- Solid
- color
- Off-white to light yellow
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CB-1158 Usage And Synthesis
Uses
(3R,4S)-3-Amino-1-[(2S)-2-amino-1-oxopropyl]-4-(3-boronopropyl)-3-pyrrolidinecarboxylic Acid Dihydrochloride is a salt analog of (3R,4S)-3-Amino-1-[(2S)-2-amino-1-oxopropyl]-4-(3-boronopropyl)-3-pyrrolidinecarboxylic Acid (CAS# 2095732-06-0), which inhibits arginase 1 (Arg1) enzyme and blocks myeloid cell-??mediated immune suppression in the tumor microenvironment.
CB-1158Supplier
ShangHai Caerulum Pharma Discovery Co., Ltd.
- Tel
- 18149758185 18149758185
- sales-cpd@caerulumpharma.com
Shanghai Lollane Biological Technology Co.,Ltd.
- Tel
- 021-52996696，15000506266 15000506266
Shanghai EFE Biological Technology Co., Ltd.
- Tel
- 021-65675885 18964387627
- info@efebio.com
Shanghai Shanyuan pharmaceutical technology co., LTD
- Tel
- 021-31761238 13167072949
- 3146446224@qq.com
Nanjing Xinmeihe Pharmaceutical Co., Ltd.
- Tel
- 025-57672321 13739186949
- 2548785915@qq.com