alfa alfa di methyl phenyl acetic acid Chemical Properties

form 

Solid

color 

Brown to dark brown

InChI

InChI=1S/C20H24BF2N5O/c1-26(2)13-12-25-20(29)10-8-15-5-6-16-14-17-7-9-19(18-4-3-11-24-18)28(17)21(22,23)27(15)16/h3-7,9,11,14,24H,8,10,12-13H2,1-2H3,(H,25,29)

InChIKey

DYYUXMKNXUZBMO-UHFFFAOYSA-N

SMILES

[F-][B+3]1([N-]2C(=CC=C2C=C2C=CC(C3NC=CC=3)=N12)CCC(=O)NCCN(C)C)[F-]

alfa alfa di methyl phenyl acetic acid Usage And Synthesis

Uses

LysoTracker Red is a Red fluorescently labeled lysosomal probe with a maximum excitation/emission wavelength of 577/590 nm. The structure is composed of a fluorescein group and linked weak bases, which can freely cross the cell membrane and gather on spherical organelles. It is suitable for observing the internal biosynthesis and related pathogenesis of lysosomes[1].

References

[1] Price OT, et al. Quantitative fluorescence of 5-FU-treated fetal rat limbs using confocal laser scanning microscopy and Lysotracker Red. Cytometry A. 2003;53(1):9-21. DOI:10.1002/cyto.a.10036
[2] Pereira LC, et al. An autophagic process is activated in HepG2 cells to mediate BDE-100-induced toxicity. Toxicology. 2017;376:59-65. DOI:10.1016/j.tox.2016.05.022
[3] Nagahama M, et al. Cellular vacuolation induced by Clostridium perfringens epsilon-toxin. FEBS J. 2011;278(18):3395-3407. DOI:10.1111/j.1742-4658.2011.08263.x