20-Hydroxyganoderic acid G
20-Hydroxyganoderic acid G Basic information
- Product Name:
- 20-Hydroxyganoderic acid G
- Synonyms:
-
- 20-Hydroxyganoderic acid G
- Lanost-8-en-26-oic acid, 3,7,12,20-tetrahydroxy-11,15,23-trioxo-, (3β,7β,12β)-
- 20-Hydroxyganoderic acid G, 10 mM in DMSO
- 20-Hydroxyganoderic acid G cas
- CAS:
- 400604-12-8
- MF:
- C30H44O9
- MW:
- 548.67
- Mol File:
- 400604-12-8.mol
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20-Hydroxyganoderic acid G Chemical Properties
- Boiling point:
- 760.1±60.0 °C(Predicted)
- Density
- 1.31±0.1 g/cm3(Predicted)
- pka
- 4.80±0.23(Predicted)
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20-Hydroxyganoderic acid G Usage And Synthesis
Uses
20-Hydroxyganoderic Acid G is a lanostane triterpenoid obtained from the EtOH extract of fruiting bodies of the Ganoderma curtisii. 20-Hydroxyganoderic Acid G inhibits BV-2 microglia cells activated by LPS with an IC50 of 21.33 μM. 20-Hydroxyganoderic Acid G has therapeutic potential in the agent discovery of nerve inflammation diseases associated with microglia activated by LPS[1].
References
[1] Jiao Y, et al. Lanostane triterpenoids from Ganoderma curtisii and their NO production inhibitory activities of LPS-induced microglia. Bioorg Med Chem Lett. 2016 Aug 1;26(15):3556-61. DOI:10.1016/j.bmcl.2016.06.023
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