O-DESMETHYL TRAMADOL HCL
O-DESMETHYL TRAMADOL HCL Basic information
- Product Name:
- O-DESMETHYL TRAMADOL HCL
- Synonyms:
-
- O-DESMETHYL TRAMADOL HCL
- Phenol, 3-[(1R,2R)-2-[(dimethylamino)methyl]-1-hydroxycyclohexyl]-, rel-
- Desmethyltramadol
- O-Desmethyl Tramadol DISCONTINUED. Please offer D294740
- (+)-O-Desmethyl TramadolQ: What is (+)-O-Desmethyl Tramadol Q: What is the CAS Number of (+)-O-Desmethyl Tramadol Q: What is the storage condition of (+)-O-Desmethyl Tramadol Q: What are the applications of (+)-O-Desmethyl Tramadol
- (-) O Desmethyl Tramadol D6Q: What is (-) O Desmethyl Tramadol D6 Q: What is the CAS Number of (-) O Desmethyl Tramadol D6 Q: What is the storage condition of (-) O Desmethyl Tramadol D6 Q: What are the applications of (-) O Desmethyl Tramadol D6
- (+) O Desmethyl Tramadol D6Q: What is (+) O Desmethyl Tramadol D6 Q: What is the CAS Number of (+) O Desmethyl Tramadol D6 Q: What is the storage condition of (+) O Desmethyl Tramadol D6 Q: What are the applications of (+) O Desmethyl Tramadol D6
- O-Desmethyltramadol, O-DSMT
- CAS:
- 80456-81-1
- MF:
- C15H23NO2
- MW:
- 249.35
- Mol File:
- 80456-81-1.mol
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O-DESMETHYL TRAMADOL HCL Chemical Properties
- Boiling point:
- 403.3±25.0 °C(Predicted)
- Density
- 1.104±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- 10.00±0.10(Predicted)
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O-DESMETHYL TRAMADOL HCL Usage And Synthesis
Uses
O-Demethyltramadol is a primary active metabolite of Tramadol. O-Demethyltramadol is mainly responsible for its μ-opioid receptor-related analgesic effect. Tramadol is metabolized to O-Demethyltramadol mainly by the cytochrome P450 (CYP) 2D6 enzyme[1].
Definition
ChEBI: O-Desmethyltramadol is an alkylbenzene and a ring assembly.
References
[1] Lee J, et al. Population pharmacokinetic analysis of tramadol and O-desmethyltramadol with genetic polymorphism of CYP2D6. Drug Des Devel Ther. 2019;13:1751-1761. DOI:10.2147/DDDT.S199574