Basic information Safety Supplier Related

Fluo-2 AM

Basic information Safety Supplier Related

Fluo-2 AM Basic information

Product Name:
Fluo-2 AM
Synonyms:
  • Glycine, N-[2-[(acetyloxy)methoxy]-2-oxoethyl]-N-[4-[6-[(acetyloxy)methoxy]-3-oxo-3H-xanthen-9-yl]-2-[2-[2-[bis[2-[(acetyloxy)methoxy]-2-oxoethyl]amino]-5-methylphenoxy]ethoxy]phenyl]-, (acetyloxy)methyl ester
CAS:
1070771-36-6
MF:
C51H52N2O23
MW:
1060.96
Mol File:
1070771-36-6.mol
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Fluo-2 AM Chemical Properties

storage temp. 
-20°C
form 
A solid
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Fluo-2 AM Usage And Synthesis

Biological Activity

Fluo-2 AM is a cell-permeable fluorescent calcium indicator.1,2 It has been used to measure the activity of the neuropeptide Y4 receptor, as well as to detect intracellular calcium in tetrandine-stimulated primary rabbit corpus cavernosum smooth muscle cells. It binds to calcium (Kd = 290 nM) and displays excitation/emission maxima of 490/515 nm, respectively. Fluo-2 AM is also available in a cell-impermeable form .

References

1.Sliwoski, G., Schubert, M., Stichel, J., et al.Discovery of small-molecule modulators of the human Y4 receptorPLoS One11(6)e0157146(2016) 2.Liu, J.-H., Chen, J., Wang, T., et al.Effects of tetrandrine on cytosolic free calcium concentration in corpus cavernosum smooth muscle cells of rabbitsAsian J. Androl.8(4)405-409(2006)

Fluo-2 AMSupplier

Beijing Ouhe Technology Co., Ltd
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Shanghai Yifei Biotechnology Co. , Ltd.
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021-65675885 18964387627
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