Isopropyl 5-(Diphenylphosphoryl)pentanoate Chemical Properties

Boiling point:

437.2±28.0 °C(Predicted)

Density 

1.10±0.1 g/cm3(Predicted)

storage temp. 

-20°C

solubility 

DMF: 25 mg/ml,DMSO: 25 mg/ml,Ethanol: 50 mg/ml,Ethanol:PBS (pH 7.2) (1:3): 0.25 mg/ml

form 

A crystalline solid

InChI

InChI=1S/C20H25O3P/c1-17(2)23-20(21)15-9-10-16-24(22,18-11-5-3-6-12-18)19-13-7-4-8-14-19/h3-8,11-14,17H,9-10,15-16H2,1-2H3

InChIKey

NUSCAFULQNHZJJ-UHFFFAOYSA-N

SMILES

C(OC(C)C)(=O)CCCCP(C1=CC=CC=C1)(C1=CC=CC=C1)=O

Isopropyl 5-(Diphenylphosphoryl)pentanoate Usage And Synthesis

Description

Latanoprost is the isopropyl ester of 17-phenyl-13,14-dihydro prostaglandin F_2α. It is a prodrug of the free acid, which is a potent agonist of the FP receptor in the eye. Isopropyl 5-(diphenylphosphoryl)pentanoate is a potential trace impurity in commercial preparations of latanoprost.

Uses

Isopropyl 5-(Diphenylphosphoryl)pentanoate, is a derivative of 5-(Diphenylphosphinyl)pentanoic Acid (D492135).