SB 222200
SB 222200 Basic information
- Product Name:
- SB 222200
- Synonyms:
-
- 3-METHYL-2-PHENYL-N-[(1S)-1-PHENYLPROPYL]-4-QUINOLINECARBOXAMIDE
- 3-Methyl-2-phenyl-N-((1S)-1-phenylpropyl)quinoline-4-carboxamide
- SB222200//3-Methyl-2-phenyl-N-[(1S)-1-phenylpropyl]quinoline-4-carboxaMide
- (S)-3-METHYL-2-PHENYL-N-(1-PHENYLPROPYL)-4-QUINOLINECARBOXAMIDE
- SB 222200
- SB-222200; SB222200
- CS-1124
- 4-Quinolinecarboxamide, 3-methyl-2-phenyl-N-[(1S)-1-phenylpropyl]-
- CAS:
- 174635-69-9
- MF:
- C26H24N2O
- MW:
- 380.48
- Mol File:
- 174635-69-9.mol
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SB 222200 Chemical Properties
- Melting point:
- 154℃
- Boiling point:
- 553.5±50.0 °C(Predicted)
- Density
- 1.142
- storage temp.
- Sealed in dry,2-8°C
- solubility
- DMSO: ~28 mg/mL, soluble
- form
- solid
- pka
- 12.88±0.46(Predicted)
- color
- light yellow
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Safety Information
- Safety Statements
- 22-24/25
- WGK Germany
- 3
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SB 222200 Usage And Synthesis
Uses
3-Methyl-2-phenyl-N-[(1S)-1-phenylpropyl]-4-quinolinecarboxamide is a chemical agent used in the preparation of acylpiperazinyl-pyrazoles as antagonists to the NK3 receptor as antipsychotics (1,2).
Definition
ChEBI: 3-methyl-2-phenyl-N-[(1S)-1-phenylpropyl]-4-quinolinecarboxamide is a member of quinolines.
Biological Activity
Potent and selective non-peptide NK 3 receptor antagonist. K i values are 4.4, >100,000 and 250 nM for human NK 3 , NK 1 and NK 2 receptors respectively. Brain penetrant and active in vivo .
storage
Store at RT
SB 222200Supplier
J & K SCIENTIFIC LTD.
- Tel
- 010-82848833 400-666-7788
- jkinfo@jkchemical.com
3B Pharmachem (Wuhan) International Co.,Ltd.
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- 821-50328103-801 18930552037
- 3bsc@sina.com
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
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- 025-66099280 17798518460
- cfzhang@aikonchem.com
Haoyuan Chemexpress Co., Ltd.
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- 021-58950125
- info@chemexpress.com
Shanghai Aladdin Bio-Chem Technology Co.,LTD
- Tel
- 18521735133 18521732826;
- market@aladdin-e.com