SITS
SITS Basic information
- Product Name:
- SITS
- Synonyms:
-
- disodium 5-acetamido-2-[2-(4-isothiocyanato-2-sulphonatophenyl)vinyl]benzenesulphonate
- 4-ACETAMIDO-4'-ISOTHIOCYANATO-STILBENE-2 ,2'-DISULF.ACID-NA
- 4-ACETAMIDO-4'-ISOTHIOCYANATOSTILBENE-2- 2'-DISULFO
- acetamidoisothiocyanato-stilbenedisulfonic acid disodium
- 4-Acetamido-4μ-isothiocyanato-2,2μ-stilbenedisulfonic acid hydrate disodium salt
- SITS, Disodium 4-acetamido-4μ-isothiocyanato-stilben-2,2μ-disulfonate
- 4-Acetylamino-4'-isothiocyanatostilbene-2,2'-disulfonic acid disodium salt
- 5-(Acetylamino)-2-[2-(4-isothiocyanato-2-sulfophenyl)ethenyl]benzenesulfonic acid disodium salt
- CAS:
- 51023-76-8
- MF:
- C17H12N2Na2O7S3
- MW:
- 498.46
- EINECS:
- 256-919-4
- Product Categories:
-
- Aromatics
- Sulfur & Selenium Compounds
- Fluorescent Labels & Indicators
- marker
- Stilbene
- Mol File:
- 51023-76-8.mol
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SITS Chemical Properties
- Melting point:
- >300°C (dec.)
- storage temp.
- -20°C
- solubility
- Soluble in water, methanol, dimethyl sulfoxide
- form
- powder
- color
- Yellow or tan-yellow
- λmax
- 336 nm
- BRN
- 9177451
- Stability:
- Temperature sensitive - recommended storage at -20oC
- Biological Applications
- Chloride channel blockers; anion transport inhibitors; treating cancer,glaucoma,heart diseases,viral diseases
- CAS DataBase Reference
- 51023-76-8(CAS DataBase Reference)
- EPA Substance Registry System
- Benzenesulfonic acid, 5-(acetylamino)-2-[2-(4-isothiocyanato-2-sulfophenyl)ethenyl]-, disodium salt (51023-76-8)
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Safety Information
- Hazard Codes
- Xn
- Risk Statements
- 22-36/37/38-42
- Safety Statements
- 22-26-36/37
- WGK Germany
- 3
- F
- 8-10-21
- HS Code
- 2930909899
MSDS
- Language:English Provider:SigmaAldrich
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SITS Usage And Synthesis
Chemical Properties
Light Yellow Solid
Uses
A fluorescent label for the specific and reversible labelling of the outer components of the plasma membrane. The reagent reacts with a fixed number of sites on the surface of cells concerned with anion permeation; does not pass through the osmotic barrier of the membrane; reacts under physiological conditions of temperature, pH and tonicity; and is detectable in small amounts. SEE ALSO NOTES FOR DIDS (CAT#D460600). Fluorescence: max. Abs. l = 336nm, max. Em. l = 436 nm.
Uses
Fluorescent marker for membranes; inhibits anion permeability of membranes. Also inactivates Na,K-ATPase, by covalent modification of a specific Lys residue.
SITSSupplier
J & K SCIENTIFIC LTD.
- Tel
- 010-82848833 400-666-7788
- jkinfo@jkchemical.com
3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel
- 821-50328103-801 18930552037
- 3bsc@sina.com
Chemsky（shanghai）International Co.,Ltd.
- Tel
- 021-50135380
- shchemsky@sina.com
Tianjin heowns Biochemical Technology Co., Ltd.
- Tel
- 400 638 7771
- sales@heowns.com
S.Z. PhyStandard Bio-Tech. Co., Ltd.
- Tel
- 0755-83725681-603
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SITS(51023-76-8)Related Product Information
- 4-AMINOSTILBENE
- 4-Vinylanilin
- 4-Methylphenyl isothiocyanate
- TRANS-STILBENE
- 4-METHYLFORMANILIDE
- 4,4'-DIAMINOSTILBENE DIHYDROCHLORIDE
- 5-Amino-2-methylbenzenesulfonic acid
- p-Acetotoluidide
- 4,4'-Diamino-2,2'-stilbenedisulfonic acid
- SITS
- TRANS-4-AMINOSTILBENE
- N-(4-VINYL-PHENYL)-ACETAMIDE
- TRANS-4-ACETYL-AMINOSTILBENE
- P-VINYLPHENYL ISOTHIOCYANATE
- SITS AMINE
- o-Toluenesulfonic acid, sodium salt
- SITS:Ion Channels
- 4-ACETAMIDO-4'-ISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID, SODIUM SALT [SITS]